Thurau S, Pleyer U
Augenklinik, Klinikum der Universität München; Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland.
Augenklinik, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Deutschland.
Ophthalmologe. 2016 Oct;113(10):879-892. doi: 10.1007/s00347-016-0328-3.
Anterior uveitis is a potentially sight-threatening disease, which affects either one or both eyes. Although the etiology is not fully understood, important associations with systemic diseases and infections have been established. A thorough clinical investigation with the slit lamp may reveal important findings leading to diagnosis and therapy. Additional diagnostic procedures are usually required only with the occurrence of relapses. Most anterior uveitis cases with an underlying autoimmune etiology respond very well to topical steroids and mydriasis while systemic treatment is rarely needed. In contrast, infectious causes typically require systemic medication. Anterior uveitis has a good prognosis if treated adequately despite some complications like cataract, macular edema, or increase of intraocular pressure, which cannot be prevented in all cases.
前葡萄膜炎是一种可能威胁视力的疾病,可累及单眼或双眼。虽然其病因尚未完全明确,但已确定与全身性疾病和感染有重要关联。通过裂隙灯进行全面的临床检查可能会发现有助于诊断和治疗的重要线索。通常仅在复发时才需要额外的诊断程序。大多数由自身免疫病因引起的前葡萄膜炎病例对局部使用类固醇和散瞳治疗反应良好,很少需要全身治疗。相比之下,感染性病因通常需要全身用药。尽管存在一些并发症,如白内障、黄斑水肿或眼压升高,但如果治疗得当,前葡萄膜炎的预后良好,不过这些并发症在所有情况下都无法预防。