Wandrup J, Tvede K, Grinsted J, Jordening H
Department of Clinical Chemistry, Herlev Hospital, Denmark.
Clin Chem. 1989 Aug;35(8):1740-3.
A first-generation semi-automatic amperometric lactate analyzer (Yellow Springs Instrument Co.) was assessed for urgent ("stat"), rapid laboratory measurements in whole blood and cerebrospinal fluid. For whole blood, measured lactate concentration and hematocrit were linearly correlated. An improved equation is presented for estimating the concentration of lactate in plasma from measurements in whole blood. The 95% reference range for the concentration of lactate in paired samples of capillary and venous whole blood from 40 healthy laboratory adults was found to be 0.4-1.5 mmol/L and 0.3-1.5 mmol/L, respectively. The 95% ranges for lactate in whole blood from 24 uncomplicated vaginal deliveries at term were established for cord venous blood, 1.2-5.0 mmol/L; cord arterial blood, 1.6-5.5 mmol/L; and maternal venous blood, 1.7-6.6 mmol/L. The 95% paired ranges were established for 20 lumbar-anaesthetized urological patients without neurological disorders after induction of anaesthesia for venous whole blood and cerebrospinal fluid (venous blood, 0.5-1.3 mmol/L; cerebrospinal fluid, 1.1-2.4 mmol/L).
对第一代半自动安培型乳酸分析仪（黄泉仪器公司）进行了评估，以用于全血和脑脊液的紧急（“即刻”）、快速实验室测量。对于全血，测得的乳酸浓度与血细胞比容呈线性相关。提出了一个改进方程，用于根据全血测量值估算血浆中乳酸的浓度。在40名健康实验室成年志愿者中，配对的毛细血管和静脉全血样本中乳酸浓度的95%参考范围分别为0.4 - 1.5 mmol/L和0.3 - 1.5 mmol/L。对24例足月顺产无并发症产妇的全血乳酸95%范围进行了测定，脐静脉血为1.2 - 5.0 mmol/L；脐动脉血为1.6 - 5.5 mmol/L；产妇静脉血为1.7 - 6.6 mmol/L。对20例无神经系统疾病的腰麻泌尿外科患者，在麻醉诱导后，测定了静脉全血和脑脊液中乳酸的95%配对范围（静脉血为0.5 - 1.3 mmol/L；脑脊液为1.1 - 2.4 mmol/L）。
