Saiki O, Saeki Y, Tanaka T, Doi S, Hara H, Negoro S, Igarashi T, Kishimoto S
Third Department of Internal Medicine, Osaka University Medical School, Japan.
Arthritis Rheum. 1987 Nov;30(11):1289-92. doi: 10.1002/art.1780301112.
Statistical analysis of serum immunoglobulin levels in 54 systemic lupus erythematosus (SLE) patients showed a decrease in serum IgM (normal 77 +/- 26 mg/dl; P less than 0.001) that was closely related to disease duration. The longer the duration of SLE, the more striking the decrease in serum levels of IgM (r = -0.74, P less than 0.01). Selective IgM deficiency (less than 47 mg/dl) occurred in SLE patients whose disease was clinically inactive or less active.
对54例系统性红斑狼疮（SLE）患者血清免疫球蛋白水平的统计分析显示，血清IgM水平降低（正常为77±26mg/dl；P<0.001），且这与疾病持续时间密切相关。SLE病程越长，血清IgM水平下降越显著（r = -0.74，P<0.01）。选择性IgM缺乏（低于47mg/dl）发生在临床病情不活动或活动程度较低的SLE患者中。
