Copeland Jan, Gates Peter, Pokorski Izabella
22-32 King Street, Randwick, NSW 2031, Australia.
Curr Pharm Des. 2016;22(42):6397-6408. doi: 10.2174/1381612822666160831094811.
As policy responses to cannabis use and availability change internationally, levels of cannabis use disorder rise and treatment seeking increases. Diversion to cannabis treatment from the criminal justice system also increases demand in the system. At a time of developing treatment systems in response to this demand, an understanding of the evidence is increasingly important.
To provide a narrative review of the developing evidence-base for psycho-social interventions for cannabis use disorder, including adjunctive cannabinoid agonist therapy.
Two researchers independently conducted a literature search for articles published prior to February 2016, located through online search of four electronic databases (Google Scholar, CINAHL, Medline, and PsycINFO). Only randomised controlled trials describing treatment(s) for cannabis use or cannabis use disorder with a measure of either cannabis use frequency or cannabis use disorder severity were included. Non-English papers, review papers, posters, opinion pieces, letters or editorials, case studies (N<10) and published abstracts were excluded.
The cannabis treatment most likely to be effective for adolescents and adults is based on the combination of Motivational Enhancement Therapy (MET) and Cognitive Behavioural Therapy (CBT) with the inclusion of contingency management and agonist replacement therapy showing promise.
A more concrete and robust evidence base is required for these interventions. Replication of treatment studies is needed using standardised interventions, methods and measures to minimise conflicting findings, inconsistent follow-up periods and relatively poor treatment effects over time.
随着国际上针对大麻使用和可得性的政策措施不断变化,大麻使用障碍的发生率上升,寻求治疗的人数也在增加。从刑事司法系统转向大麻治疗也增加了该系统的需求。在为应对这一需求而发展治疗体系之际,了解相关证据变得越来越重要。
对大麻使用障碍心理社会干预措施(包括辅助性大麻素激动剂疗法)的现有证据进行叙述性综述。
两名研究人员独立检索了2016年2月之前发表的文章,通过在线搜索四个电子数据库(谷歌学术、护理学与健康领域数据库、医学索引数据库和心理学文摘数据库)获取。仅纳入描述针对大麻使用或大麻使用障碍的治疗且有大麻使用频率或大麻使用障碍严重程度测量指标的随机对照试验。排除非英文论文、综述论文、海报、观点文章、信件或社论、案例研究(N<10)以及已发表的摘要。
对青少年和成年人最有效的大麻治疗方法是将动机增强疗法(MET)和认知行为疗法(CBT)相结合,同时应急管理和激动剂替代疗法也显示出前景。
这些干预措施需要更具体、更有力的证据基础。需要使用标准化干预措施、方法和测量指标对治疗研究进行重复,以尽量减少相互矛盾的结果、不一致的随访期以及随着时间推移相对较差的治疗效果。