Peng F, Xue C-H, Hwang S K, Li W-H, Chen Z, Zhang J-Z
Department of Dermatology, Peking University People's Hospital, Beijing, China.
J Eur Acad Dermatol Venereol. 2017 Feb;31(2):355-360. doi: 10.1111/jdv.13834. Epub 2016 Sep 5.
Skin ageing especially senile lentigo directly affects self-esteem. For decades, senile lentigo has been associated with chronic exposure to solar radiation. However, a study conducted recently in Caucasian subjects suggested that exposure to air pollution was significantly correlated with extrinsic skin ageing, in particular senile lentigines.
To investigate the association between fine particulate matter (PM ) and skin ageing, particularly senile lentigo and seborrheic keratosis.
The study enrolled 400 Chinese women aged 40-90 years including 210 from the Yanqing county in Beijing (low PM exposure group) and 190 from the Xuanwumen in Beijing (high PM exposure group). Skin ageing symptoms, particularly senile lentigines and seborrheic keratoses, were clinically assessed using scores of intrinsic and extrinsic skin ageing. An ordinal logistic regression model was used to analyse the effect of PM on skin ageing adjusted for factors underlying skin ageing.
In the study population of Xuanwumen, we found that senile lentigo on cheeks and back of hands was 1.48 times and 2.8 times higher, respectively, compared with those from Yanqing county. However, no association was found between PM and seborrheic keratosis. We found that other variables such as smoking, second-hand smoking, contact with fossil fuels and skin types were significantly associated with skin ageing.
These results indicate that PM was another extrinsic factor promoting skin ageing.
皮肤老化尤其是老年斑直接影响自尊。几十年来，老年斑一直与长期暴露于太阳辐射有关。然而，最近一项针对白种人的研究表明，暴露于空气污染与皮肤外源性老化显著相关，尤其是老年斑。
研究细颗粒物（PM）与皮肤老化之间的关联，特别是老年斑和脂溢性角化病。
该研究招募了400名年龄在40至90岁之间的中国女性，其中210名来自北京延庆县（低PM暴露组），190名来自北京宣武门（高PM暴露组）。使用皮肤内源性和外源性老化评分对皮肤老化症状，特别是老年斑和脂溢性角化病进行临床评估。采用有序逻辑回归模型分析PM对皮肤老化的影响，并对皮肤老化的潜在因素进行校正。
在宣武门的研究人群中，我们发现脸颊和手背上的老年斑分别比延庆县的人群高1.48倍和2.8倍。然而，未发现PM与脂溢性角化病之间存在关联。我们发现吸烟、二手烟、接触化石燃料和皮肤类型等其他变量与皮肤老化显著相关。
这些结果表明，PM是促进皮肤老化的另一个外源性因素。
