Saha N, Bhattacharyya S P
Department of Biochemistry, Faculty of Medicine, National University of Singapore.
Hum Hered. 1989;39(2):110-2. doi: 10.1159/000153844.
Autopsy liver samples from 244 Chinese, 119 Malays and 136 Indians were screened for glutamate-pyruvate transaminase (GPT) subtypes by starch-gel electrophoresis and isoelectric focusing at pH 5-7. Altogether, ten phenotypes controlled by four alleles (GPT1, GPT2A, GPT2B and GPT3) were identified. There was no significant difference in the frequency of GPT alleles between the ethnic groups. The distribution of GPT types was in agreement with the Hardy-Weinberg equilibrium in all the ethnic groups.
通过淀粉凝胶电泳和pH 5 - 7的等电聚焦，对244名中国人、119名马来人和136名印度人的尸检肝脏样本进行谷氨酸丙酮酸转氨酶（GPT）亚型筛查。总共鉴定出由四个等位基因（GPT1、GPT2A、GPT2B和GPT3）控制的十种表型。不同种族之间GPT等位基因频率没有显著差异。所有种族中GPT类型的分布均符合哈迪-温伯格平衡。
