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丙氨酸转氨酶(E.C.2.7.6.1)的多态性:常见和罕见等位基因。

Polymorphism of alanine aminotransferase (E.C.2.7.6.1): common and rare alleles.

作者信息

Kömpf J, Ritter H

出版信息

Hum Genet. 1979 Oct 2;51(3):287-92. doi: 10.1007/BF00283396.

Abstract

Gene frequencies of common and rare GPT alleles derived from an investigation of 1139 unrelated, healthy individuals from southwestern Germany are given. GPT typing was performed by means of horizontal starch gel electrophoresis in a Tris-histidine x HCl buffer system. In addition, a new electrophoretic variant, GPT9, is described. The frequencies of the GPT alleles observed were calculated as: GPT1, 0.4987; GPT2, 0.4686; GPT1M, 0.022; GPT0, 0.005; GPT3, 0.0022; GPT4, 0.0025; GPT8, 0.0005; GPT9, 0.0005.

摘要

给出了对来自德国西南部1139名无亲缘关系的健康个体进行调查得出的常见和罕见谷丙转氨酶(GPT)等位基因的基因频率。GPT分型是在Tris - 组氨酸×盐酸缓冲系统中通过水平淀粉凝胶电泳进行的。此外,还描述了一种新的电泳变体GPT9。观察到的GPT等位基因频率计算如下:GPT1,0.4987;GPT2,0.4686;GPT1M,0.022;GPT0,0.005;GPT3,0.0022;GPT4,0.0025;GPT8,0.0005;GPT9,0.0005。

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