Ris I, Søgaard K, Gram B, Agerbo K, Boyle E, Juul-Kristensen B
Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark; Metropolitan University College, Tagensvej 18, 2200 Copenhagen N, Denmark.
Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.
Man Ther. 2016 Dec;26:132-140. doi: 10.1016/j.math.2016.08.004. Epub 2016 Aug 20.
To investigate the effect of combining pain education, specific exercises and graded physical activity training (exercise) compared with pain education alone (control) on physical health-related quality of life (HR-QoL) in chronic neck pain patients.
A multicentre randomised controlled trial of 200 neck pain patients receiving pain education. The exercise group received additional exercises for neck/shoulder, balance and oculomotor function, plus graded physical activity training. Patient-reported outcome measures (Short Form-36 Physical and Mental component summary scores, EuroQol-5D, Beck Depression Inventory-II, Neck Disability Index, Pain Bothersomeness, Patient-Specific Functioning Scale, Tampa Scale of Kinesiophobia, Global Perceived Effect) and clinical tests (Aastrand Physical Fitness, cervical Range of Motion, Pressure Pain Threshold at infraspinatus, tibialis anterior and cervical spine, Cranio-cervical Flexion, Cervical Extension muscle function, and oculomotion) were recorded at baseline and after 4 months.
The exercise group showed statistically significant improvement in physical HR-QoL, mental HR-QoL, depression, cervical pressure pain threshold, cervical extension movement, muscle function, and oculomotion. Per protocol analyses confirmed these results with additional significant improvements in the exercise group compared with controls.
This multimodal intervention may be an effective intervention for chronic neck pain patients.
The trial was registered on www.ClinicalTrials.govNCT01431261 and at the Regional Scientific Ethics Committee of Southern Denmark S-20100069.
探讨疼痛教育、特定锻炼和分级体育活动训练（锻炼组）与单纯疼痛教育（对照组）相比，对慢性颈部疼痛患者与身体健康相关的生活质量（HR-QoL）的影响。
一项针对200名接受疼痛教育的颈部疼痛患者的多中心随机对照试验。锻炼组接受了针对颈部/肩部、平衡和动眼功能的额外锻炼，以及分级体育活动训练。在基线和4个月后记录患者报告的结局指标（简短36项健康调查量表的身体和心理成分汇总得分、欧洲五维健康量表、贝克抑郁量表第二版、颈部功能障碍指数、疼痛困扰程度、患者特定功能量表、坦帕运动恐惧量表、总体感知效果）和临床测试（阿斯兰德体能测试、颈椎活动范围、冈下肌、胫骨前肌和颈椎的压痛阈值、颅颈屈曲、颈椎伸展肌肉功能和眼球运动）。
锻炼组在身体HR-QoL、心理HR-QoL、抑郁、颈椎压痛阈值、颈椎伸展运动、肌肉功能和眼球运动方面有统计学意义的改善。符合方案分析证实了这些结果，锻炼组与对照组相比有额外的显著改善。
这种多模式干预可能是慢性颈部疼痛患者的一种有效干预措施。
该试验在www.ClinicalTrials.gov上注册，注册号为NCT01431261，并在丹麦南部地区科学伦理委员会注册，编号为S-20100069。
