Couppé C, Comins J, Beyer N, Hansen S E, Stodolsky D S, Siersma V
Musculoskeletal Rehabilitation Research Unit, Department of Physical Therapy, Bispebjerg Hospital, Copenhagen, Denmark.
IOC Sports Medicine, Department of Orthopaedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Building 8, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.
Qual Life Res. 2017 Feb;26(2):381-391. doi: 10.1007/s11136-016-1402-7. Epub 2016 Sep 6.
Multidisciplinary rehabilitation has beneficial effects on health-related quality of life (HRQoL) in patients with chronic rheumatic diseases. However, whether this intervention benefits different age groups in women or men is largely unknown.
To investigate HRQoL in patients with chronic rheumatic disease after completion of a 3-week multidisciplinary treatment, with special focus on differences in effect between age and gender groups.
HRQoL was measured with SF-36. Mean scores for all SF-36 domains were compared before and after the 3-week regimen and again at 3-, 6-, and 12-month follow-ups. Multivariable linear regression models using generalized estimating equations to account for repeated measurement were employed. A weighting procedure to account for differential dropouts was applied.
Three hundred fifty-six women and 74 men with chronic rheumatic disease were included. There were short-term improvements in all SF-36 domains irrespective of age or gender. These effects persisted for up to 1 year in the psychological, social, and energy domains for women under 50. We found no lasting effects for men; however, young men showed similar trends.
Inpatient multidisciplinary rehabilitation improves short-term HRQoL in all patients. Younger women maintain these beneficial effects for up to 1 year. Additional intervention should be considered for elderly women and for men in order to sustain rehabilitation effects.
多学科康复对慢性风湿性疾病患者的健康相关生活质量(HRQoL)具有有益影响。然而,这种干预对不同年龄组的女性或男性是否有益在很大程度上尚不清楚。
调查慢性风湿性疾病患者在完成为期3周的多学科治疗后的健康相关生活质量,特别关注年龄和性别组之间的效果差异。
使用SF-36量表测量健康相关生活质量。在为期3周的治疗方案前后以及在3个月、6个月和12个月的随访时比较所有SF-36领域的平均得分。采用使用广义估计方程来考虑重复测量的多变量线性回归模型。应用加权程序来考虑不同的失访情况。
纳入了356名患有慢性风湿性疾病的女性和74名男性。无论年龄或性别,所有SF-36领域均有短期改善。对于50岁以下的女性,这些影响在心理、社会和精力领域持续长达1年。我们发现男性没有持久影响;然而,年轻男性表现出类似趋势。
住院多学科康复改善了所有患者的短期健康相关生活质量。年轻女性可将这些有益影响维持长达1年。应为老年女性和男性考虑额外的干预措施,以维持康复效果。