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急性心肌梗死后二级预防面临的挑战:行动呼吁。

Challenges in secondary prevention after acute myocardial infarction: A call for action.

作者信息

Piepoli Massimo F, Corrà Ugo, Dendale Paul, Frederix Ines, Prescott Eva, Schmid Jean Paul, Cupples Margaret, Deaton Christi, Doherty Patrick, Giannuzzi Pantaleo, Graham Ian, Hansen Tina Birgitte, Jennings Catriona, Landmesser Ulf, Marques-Vidal Pedro, Vrints Christiaan, Walker David, Bueno Héctor, Fitzsimons Donna, Pelliccia Antonio

机构信息

1 Cardiac Department, Guglielmo da Saliceto Polichirurgico Hospital AUSL Piacenza, Italy.

2 Cardiology Rehabilitation Division, Scientific Institute of Veruno, Italy.

出版信息

Eur J Prev Cardiol. 2016 Dec;23(18):1994-2006. doi: 10.1177/2047487316663873. Epub 2016 Sep 27.

Abstract

Worldwide, each year more than 7 million people experience myocardial infarction, in which one-year mortality rates are now in the range of 10%, but vary with patient characteristics. The consequences are even more dramatic: among patients who survive, 20% suffer a second cardiovascular event in the first year and approximately 50% of major coronary events occur in those with a previous hospital discharge diagnosis of ischaemic heart disease. The people behind these numbers spur this call for action. Prevention after myocardial infarction is crucial to reduce risk and suffering. Evidence-based interventions include optimal medical treatment with anti-platelets and statins, achievement of blood pressure, lipid and blood glucose targets, and appropriate lifestyle changes. The European Society of Cardiology and its constituent bodies are determined to embrace this challenge by developing a consensus document in which the existing gaps for secondary prevention strategies are reviewed. Effective interventions in relation to the patients, healthcare providers and healthcare systems are proposed and discussed. Finally, innovative strategies in hospital as well as in outpatient and long-term settings are endorsed.

摘要

在全球范围内,每年有超过700万人发生心肌梗死,目前其一年死亡率在10%左右,但会因患者特征而有所不同。后果更为严重:在存活的患者中,20%在第一年发生第二次心血管事件,约50%的主要冠状动脉事件发生在既往出院诊断为缺血性心脏病的患者中。这些数字背后的人们促使发出这一行动呼吁。心肌梗死后的预防对于降低风险和减轻痛苦至关重要。基于证据的干预措施包括使用抗血小板药物和他汀类药物进行优化药物治疗、实现血压、血脂和血糖目标以及进行适当的生活方式改变。欧洲心脏病学会及其下属机构决心通过制定一份共识文件来应对这一挑战,该文件将对二级预防策略中存在的差距进行审查。提出并讨论了针对患者、医疗服务提供者和医疗系统的有效干预措施。最后,认可了医院以及门诊和长期环境中的创新策略。

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