Dutta Moumita, Bhalla Amar S, Guo Ruyan
Department of Electrical and Computer Engineering, University of Texas at San Antonio , San Antonio, Texas.
Adv Wound Care (New Rochelle). 2016 Aug 1;5(8):338-348. doi: 10.1089/wound.2015.0685.
This review article puts together all the studies performed so far in realizing terahertz (THz) spectra as a probing mechanism for burn evaluation, summarizing their experimental conditions, observations, outcomes, merits, and demerits, along with a comparative discussion of other currently used technologies to present the state of art in a condensed manner. The key features of this noncontact investigation technique like its precise burn depth analysis and the approaches it follows to convert the probed data into a quantitative measure have also been discussed in this article. The current research developments in THz regime observed in device design technologies (like THz time domain spectrometer, quantum cascade THz lasers, THz single-photon detectors, etc.) and in understanding its unique properties (like nonionizing nature, penetrability through dry dielectrics, etc.) have motivated the research world to realize THz window as a potential candidate for burn detection. Application of appropriate medical measure for burn injury is primarily subjective to proper estimation of burn depth. Tool modality distinguishing between partial and full-thickness burn contributing toward correct medical care is indeed awaited. The overview of THz imaging as a burn assessment tool as provided in this article will certainly help in further nurturing of this emerging diagnostic technique particularly in improving its detection and accompanied image processing methods so that the minute nuances captured by the THz beam can be correlated with the physiological-anatomical changes in skin structures, caused by burn, for better sensitivity, resolution, and quantitative analysis.
这篇综述文章汇总了迄今为止所有关于实现太赫兹(THz)光谱作为烧伤评估探测机制的研究,总结了它们的实验条件、观察结果、成果、优点和缺点,同时对其他当前使用的技术进行了比较讨论,以简洁的方式呈现了当前的技术水平。本文还讨论了这种非接触式检测技术的关键特性,如其精确的烧伤深度分析以及将探测数据转换为定量测量的方法。在器件设计技术(如太赫兹时域光谱仪、量子级联太赫兹激光器、太赫兹单光子探测器等)以及理解其独特性质(如非电离性质、通过干电介质的穿透性等)方面观察到的太赫兹领域当前的研究进展,促使研究界将太赫兹窗口视为烧伤检测的潜在候选者。对烧伤损伤采取适当的医疗措施主要取决于对烧伤深度的正确估计。确实需要能够区分部分厚度烧伤和全层厚度烧伤以有助于正确医疗护理的工具形式。本文提供的关于太赫兹成像作为烧伤评估工具的概述肯定会有助于进一步培育这种新兴的诊断技术,特别是在改进其检测和伴随的图像处理方法方面,以便太赫兹光束捕捉到的细微差别能够与烧伤引起的皮肤结构的生理 - 解剖变化相关联,从而实现更好的灵敏度、分辨率和定量分析。