Özel Rıfat Emrah, Kahnemouyi Sina, Fan Hsinwen, Mak Wai Han, Lohith Akshar, Seger Adam, Teodorescu Mircea, Pourmand Nader
Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064.
Computer Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064.
ACS Sens. 2016 Mar 25;1(3):265-271. doi: 10.1021/acssensors.5b00289. Epub 2016 Jan 5.
In this report, we demonstrated a handheld wireless voltage-clamp amplifier for current measurement of nanopore sensors. This amplifier interfaces a sensing probe and connects wirelessly with a computer or smartphone for the required stimulus input, data processing and storage. To test the proposed Signal Transduction by Ion Nanogating (STING) wireless amplifier, in the current study the system was tested with a nano-pH sensor to measure pH of standard buffer solutions and the performance was compared against the commercial voltage-clamp amplifier. To our best knowledge, STING amplifier is the first miniaturized wireless voltage-clamp platform operated with a customized smart-phone application (app).
在本报告中,我们展示了一种用于纳米孔传感器电流测量的手持式无线电压钳放大器。该放大器连接传感探头,并与计算机或智能手机无线连接,以进行所需的刺激输入、数据处理和存储。为了测试所提出的离子纳米门控信号转导(STING)无线放大器,在当前研究中,该系统使用纳米pH传感器进行测试,以测量标准缓冲溶液的pH值,并将性能与商用电压钳放大器进行比较。据我们所知,STING放大器是首个通过定制智能手机应用程序(app)运行的小型化无线电压钳平台。