Probst S, Weller C D, Bobbink P, Saini C, Pugliese M, Skinner Monika Buehrer, Gethin G
HES-SO University of Applied Sciences and Arts Western Switzerland, School of Health Sciences, Avenue de Champel 47, 1206, Geneva, Switzerland.
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, The Alfred Hospital, Monash University, Melbourne, Australia.
Syst Rev. 2021 May 12;10(1):148. doi: 10.1186/s13643-021-01697-3.
Venous leg ulcers (VLUs) are chronic wounds characterized by slow healing and high recurrence. Information on prevalence and incidence is essential for ascertaining the burden of VLU on the health care system and to inform epidemiological research, priority setting, and health care planning. The objective of this protocol is to present a transparent process for how we plan to review the existing international literature on the prevalence and incidence of VLU as well as the characteristics of the population reported within these studies.
An exploratory search was performed using MEDLINE via PubMed and CINHAL via Ebsco to identify concepts, keywords, MeSH terms, and headings to identify study types looking at data of VLU prevalence and/or incidence and related patient characteristics. The findings of this exploratory search will determine the final search strategy. The titles and abstracts of the identified articles will be screened independently be two authors for relevance. Study which pass the quality assessment will be included. Data extraction will be performed independently by two authors and in accordance with a pre-designed data extraction form. If the data allows, a meta-analysis will be performed otherwise a descriptive summary of the findings will be conducted.
The results of this review will contribute to the evidence base on VLU occurrence and may inform the decision making of healthcare professionals, policy-makers, and consumers. It will also inform future research in this area of VLU care.
PROSPERO CRD42020205855.
下肢静脉溃疡（VLU）是一种慢性伤口，其特点是愈合缓慢且复发率高。患病率和发病率信息对于确定VLU对医疗保健系统的负担以及为流行病学研究、优先事项设定和医疗保健规划提供依据至关重要。本方案的目的是介绍一个透明的过程，说明我们计划如何回顾关于VLU患病率和发病率的现有国际文献，以及这些研究中报告的人群特征。
通过PubMed使用MEDLINE以及通过Ebsco使用CINHAL进行探索性检索，以确定概念、关键词、医学主题词（MeSH）和标题，从而识别研究类型，以查找有关VLU患病率和/或发病率以及相关患者特征的数据。该探索性检索的结果将决定最终的检索策略。两名作者将独立筛选已识别文章的标题和摘要以确定其相关性。通过质量评估的研究将被纳入。数据提取将由两名作者独立进行，并按照预先设计的数据提取表进行。如果数据允许，将进行荟萃分析，否则将对结果进行描述性总结。
本次综述的结果将有助于建立关于VLU发生情况的证据基础，并可能为医疗保健专业人员、政策制定者和消费者的决策提供参考。它还将为VLU护理领域的未来研究提供信息。
PROSPERO CRD42020205855。
