向大鼠脑室内注射蛙皮素可抑制其胆汁和胃液分泌。
Intracerebroventricular administration of bombesin inhibits biliary and gastric secretion in the rat.
作者信息
Yao C Z, MacLellan D G, Thompson J C
机构信息
Department of Surgery, University of Texas Medical Branch, Galveston 77550.
出版信息
J Neurosci Res. 1989 Apr;22(4):461-3. doi: 10.1002/jnr.490220412.
PMID:2760944
Abstract
The effect of intracerebroventricular (ICV) bombesin on bile and gastric acid secretion was examined in the rat. ICV bombesin (10 micrograms in 10 microliters) inhibited basal biliary volume by 27% and bile bicarbonate by 52% of control values, while gastric acid secretion was decreased by 75%. These results provide evidence for central mechanisms for the control of gastrointestinal function.
摘要
研究了大鼠脑室内注射蛙皮素对胆汁和胃酸分泌的影响。脑室内注射蛙皮素（10微升含10微克）使基础胆汁分泌量比对照值降低了27%，胆汁碳酸氢盐降低了52%，而胃酸分泌减少了75%。这些结果为控制胃肠功能的中枢机制提供了证据。
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