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2型糖尿病患者中胃轻瘫相关症状的患病率及危险因素

Prevalence and risk factors of gastroparesis-related symptoms among patients with type 2 diabetes.

作者信息

Almogbel Rakan A, Alhussan Fulwa A, Alnasser Sulaiman A, Algeffari Metab A

机构信息

Qassim University College of Medicine, Email:

Diabetologist Consultant, Assistant Professor of Family Medicine, Qassim University - College of Medicine, Email:

出版信息

Int J Health Sci (Qassim). 2016 Jul;10(3):397-404.

PMID:27610063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5003583/
Abstract

BACKGROUND

The prevalence of gastroparesis in type 2 diabetes mellitus (T2DM) vary widely. Our aim is to estimate the prevalence of clinical symptoms of gastroparesis among patients with type 2 diabetes mellitus and explore the relationship between gastroparesis and other risk factors.

METHODS

A cross-sectional study evaluating 147 type 2 diabetics using the Gastroparesis Cardinal Symptoms Index (GCSI). A GCSI Total Score ≥ 1.90 were chosen as having definite symptoms of gastroparesis. All patients completed a demographic questionnaire and interviewed to complete the. Demographic Data, disease duration, Medication, comorbidities, recent blood glucose and HbA1C were collected and investigated.

RESULTS

The prevalence of clinical symptoms of gastroparesis among type 2 diabetics was 10.8%. Clinical symptoms of gastroparesis were significantly correlated to HbA1c (p=0.001), blood glucose (p= 0.003), duration of diabetes (p= 0.02) and comorbidities (p=0.009). The most common symptoms were bloating, stomach fullness and early satiety (63.94%, 55.1% and 48.3% respectively). In logistic regression analysis, female gender emerged as significant independent predictors of the presence of at least one symptom.

CONCLUSIONS

The prevalence of clinical symptoms of gastroparesis observed in the Saudi patientsdiagnosedwithtype2 diabetes was 10.8% and is independently associated with poor controlled diabetes, hyperglycemia, and long duration of diabetes and history of Co-morbid conditions.

摘要

背景

2型糖尿病(T2DM)患者中胃轻瘫的患病率差异很大。我们的目的是评估2型糖尿病患者中胃轻瘫临床症状的患病率,并探讨胃轻瘫与其他危险因素之间的关系。

方法

一项横断面研究,使用胃轻瘫主要症状指数(GCSI)对147例2型糖尿病患者进行评估。GCSI总分≥1.90被选为有明确胃轻瘫症状。所有患者完成一份人口统计学问卷并接受访谈以完成调查。收集并调查人口统计学数据、疾病持续时间、用药情况、合并症、近期血糖和糖化血红蛋白(HbA1C)。

结果

2型糖尿病患者中胃轻瘫临床症状的患病率为10.8%。胃轻瘫的临床症状与糖化血红蛋白(p=0.001)、血糖(p=0.0.003)、糖尿病病程(p=0.02)和合并症(p=0.009)显著相关。最常见的症状是腹胀、胃部饱胀和早饱(分别为63.94%、55.1%和48.3%)。在逻辑回归分析中,女性成为至少有一种症状存在的显著独立预测因素。

结论

在沙特被诊断为2型糖尿病的患者中观察到的胃轻瘫临床症状患病率为10.8%,并且与糖尿病控制不佳、高血糖、糖尿病病程长和合并症病史独立相关。

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