Franco Ademir, Segato André V K, Couto Soraya A B, Rodrigues Johann Aline Cristina Batista, Friedlander Arthur H, Couto Souza Paulo H
Department of Stomatology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
Department of Endodontics, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
J Dent Child (Chic). 2016;83(2):102-5.
A central giant cell granuloma (CGCG) is typically regarded as a benign lesion with osteoclastic activity. Treatment often involves surgical procedures that may cause deformities; however, minimally invasive approaches have been suggested for treating pediatric patients. We report a case of CGCG of the mandible in a 13-year-old boy who presented with a well-defined radiolucent area in the anterior mandible that was initially detected in a radiographic examination for orthodontic purposes. An incisional biopsy was performed and diagnosed histologically as a CGCG. The patient underwent clinical and radiographic follow-up only after the biopsy, eventually showing signs of bone healing. Five years later, complete resolution of the lesion was observed radiographically. Considering this optimal outcome, similar cases of CGCG should be carefully analyzed for appropriateness of this conservative approach.
中央巨细胞肉芽肿（CGCG）通常被视为一种具有破骨细胞活性的良性病变。治疗通常涉及可能导致畸形的外科手术；然而，有人建议采用微创方法治疗儿科患者。我们报告一例13岁男孩下颌骨CGCG病例，该患者下颌前部出现一个边界清晰的透光区，最初是在正畸目的的影像学检查中发现的。进行了切开活检，组织学诊断为CGCG。活检后仅对患者进行了临床和影像学随访，最终显示出骨愈合迹象。五年后，影像学观察到病变完全消退。考虑到这一理想结果，对于CGCG的类似病例，应仔细分析这种保守方法的适用性。
