使用光学相干断层扫描（OCT）对高血压患者和血压正常者的视乳头周围厚度进行形态学分析。
Morphometric Analysis of Peripapillary Thickness in Hypertensives and Normotensives using Optical Coherence Tomography (OCT).
作者信息
Addoor Krishna Rao, Bhandary Sulatha V, Rao Lavanya G, Kapoor Smita
机构信息
Professor and Head, Department of Ophthalmology, Kasturba Medical College , Manipal, Karnataka, India .
Additional Professor, Department of Ophthalmology, Kasturba Medical College , Manipal, Karnataka, India .
出版信息
J Clin Diagn Res. 2016 Jul;10(7):NC01-4. doi: 10.7860/JCDR/2016/18642.8105. Epub 2016 Jul 1.
INTRODUCTION
Hypotension following antihypertensive treatment is associated with retinal nerve fibre loss. There are studies that have reported the changes in RNFL in hypertensives.
AIM
To compare the Retinal Nerve Fibre Layer (RNFL) thickness using Optical Coherence Tomography (OCT) in hypertensive and normotensive individuals.
MATERIALS AND METHODS
The cross-sectional study was conducted from October 2012 to September 2014 to compare the RNFL thickness using SD OCT in hypertensive {no other ocular or systemic co-morbidity, vision better or equal to 6/9 (n=30)} and normotensive (n=30) individuals.
RESULTS
Statistically significant RNFL loss was detected in hypertensives (98.31 ± 7.01) when compared to the normotensives (102.51 ± 8.72) p=0.001.
CONCLUSION
Significant loss of RNFL in hypertensives point towards the altered autoregulation and warrants larger studies to assess the clinical relevance.
引言
降压治疗后的低血压与视网膜神经纤维层损失有关。已有研究报道了高血压患者视网膜神经纤维层的变化。
目的
使用光学相干断层扫描（OCT）比较高血压患者和血压正常者的视网膜神经纤维层（RNFL）厚度。
材料与方法
于2012年10月至2014年9月进行了一项横断面研究，以使用频域光学相干断层扫描（SD OCT）比较高血压患者（无其他眼部或全身合并症，视力≥6/9，n = 30）和血压正常者（n = 30）的RNFL厚度。
结果
与血压正常者（102.51±8.72）相比，高血压患者（98.31±7.01）检测到具有统计学意义的RNFL损失，p = 0.001。
结论
高血压患者RNFL的显著损失表明其自动调节功能改变，需要开展更大规模的研究来评估其临床相关性。
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