Nakamura Motoyuki, Tanaka Fumitaka, Komi Ryousuke, Tanaka Kentarou, Onodera Masayuki, Kawakami Mikio, Koeda Yorihiko, Sakai Toshiaki, Tanno Kozo, Onoda Toshiyuki, Matsura Yuki, Komatsu Takashi
Department of Internal Medicine, Iwate Medical University, Morioka, Iwate, Japan.
Department of Internal Medicine, Iwate Medical University, Morioka, Iwate, Japan.
Am J Cardiol. 2016 Nov 1;118(9):1374-1379. doi: 10.1016/j.amjcard.2016.07.055. Epub 2016 Aug 13.
This study investigated the long-term impact of the 2011 Japan earthquake and tsunami on the incidence of acute decompensated heart failure (HF) in the disaster area. This was a population-based study using comprehensive registration for all hospitals within the study area. The standardized incidence ratio (SIR) and 95% confidence interval (CI) for new onset of HF during the disaster year (2011) and postdisaster years (2012 to 2014) were determined. When SIR were compared between the low- and high-impact areas, as defined by the extent of tsunami inundation in residential areas, SIR showed a significant increase in high-impact areas in 2011 (1.67, 95% CI 1.45 to 1.88) and tended to return to baseline in 2012, the first postdisaster year (1.25, 95% CI 1.06 to 1.43). The rate again increased in 2013 (1.38, 95% CI 1.18 to 1.57) and 2014 (1.55, 95% CI 1.35 to 1.75). In low-impact areas, no such increase was apparent during either the disaster year or the postdisaster years. Mean postdisaster period SIR for municipalities significantly correlated with the percentage of tsunami flooding in residential areas (r = 0.52, p <0.05) and with the percentage of refugees within the population (r = 0.74, p <0.01). There was no significant relation between maximum seismic intensity and mean SIR in these municipalities. In conclusion, these results suggest that the catastrophic tsunami but not the earthquake per se resulted in a prolonged increase in the incidence of HF among the general population living in tsunami-stricken areas.
本研究调查了2011年日本地震及海啸对灾区急性失代偿性心力衰竭(HF)发病率的长期影响。这是一项基于人群的研究,采用了研究区域内所有医院的综合登记数据。确定了灾害年份(2011年)和灾后年份(2012年至2014年)HF新发的标准化发病率(SIR)及95%置信区间(CI)。根据居民区海啸淹没范围定义为低影响区和高影响区,并比较二者的SIR,结果显示高影响区在2011年SIR显著升高(1.67,95%CI 1.45至1.88),而在灾后第一年2012年趋于恢复至基线水平(1.25,95%CI 1.06至1.43)。2013年(1.38,95%CI 1.18至1.57)和2014年(1.55,95%CI 1.35至1.75)发病率再次升高。在低影响区,无论是灾害年份还是灾后年份,均未出现此类升高。各市政当局灾后时期的平均SIR与居民区海啸淹没百分比显著相关(r = 0.52,p <0.05),与人口中的难民百分比也显著相关(r = 0.74,p <0.01)。这些市政当局的最大地震强度与平均SIR之间无显著关系。总之,这些结果表明,灾难性海啸而非地震本身导致了生活在海啸受灾地区的普通人群中HF发病率的长期升高。