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2011年日本地震及海啸对致命性和非致命性心肌梗死发病率的长期影响

Long-Term Effects of the 2011 Japan Earthquake and Tsunami on Incidence of Fatal and Nonfatal Myocardial Infarction.

作者信息

Nakamura Motoyuki, Tanaka Kentarou, Tanaka Fumitaka, Matsuura Yuuki, Komi Ryousuke, Niiyama Masanobu, Kawakami Mikio, Koeda Yorihiko, Sakai Toshiaki, Onoda Toshiyuki, Itoh Tomonori

机构信息

Department of Internal Medicine, Iwate Medical University, Morioka, Iwate, Japan.

Department of Cardiology, Iwate Prefecture Miyako Hospital, Miyako, Iwate, Japan.

出版信息

Am J Cardiol. 2017 Aug 1;120(3):352-358. doi: 10.1016/j.amjcard.2017.05.002. Epub 2017 May 10.

Abstract

This study aimed to examine the long-term effects of the 2011 Japan earthquake and tsunami on the incidence of fatal and nonfatal myocardial infarction (MI). In the present study, the incidence of 2 types of cardiac events was comprehensively recorded. The study area was divided into 2 zones based on the severity of tsunami damage, which was determined by the percentage of the inundated area within the residential area (<10%, low-impact zone and ≥10%, high-impact zone). The standardized incidence ratio (SIR) and 95% CI for both types of cardiac events during the disaster year and the postdisaster years were determined in each zone. During the 4-year period after the disaster, the SIRs for nonfatal MI did not change to a statistically significant extent in either zones. For fatal MI, the SIR was stable during the study period in the low-impact zone. However, in the high-impact zone, the SIR was significantly elevated in the disaster year of 2011 (1.80 [95% CI 1.32 to 2.28]), and this increase was sustained for the following 3 years (2012, 2.06 [1.55 to 2.57]; 2013, 1.99 [1.49 to 2.48]; 2014, 2.12 [1.62 to 2.63]). The SIRs for fatal MI for the 4 postdisaster years in the municipal areas were significantly correlated with the percentage of the inundated area (r = 0.83; p <0.001) and the number of deaths due to the tsunami (r = 0.77; p <0.005) but not with the maximum seismic intensity (r = 0.43; p = 0.12). In conclusion, these results suggest that the devastating tsunami was associated with a continual increase in the incidence of fatal MI among disaster survivors.

摘要

本研究旨在探讨2011年日本地震及海啸对致命性和非致命性心肌梗死(MI)发病率的长期影响。在本研究中,全面记录了2种心脏事件的发病率。研究区域根据海啸破坏的严重程度分为2个区域,海啸破坏程度由居民区淹没面积的百分比确定(<10%,低影响区;≥10%,高影响区)。在每个区域确定了灾难年份及灾后年份这2种心脏事件的标准化发病率(SIR)及95%置信区间(CI)。在灾难后的4年期间,非致命性MI的SIR在两个区域均未发生具有统计学意义的变化。对于致命性MI,在低影响区,SIR在研究期间保持稳定。然而,在高影响区,2011年灾难年份的SIR显著升高(1.80 [95%CI 1.32至2.28]),且这种升高在随后3年持续存在(2012年,2.06 [1.55至2.57];2013年,1.99 [1.49至2.48];2014年,2.12 [1.62至2.63])。市政区域灾后4年致命性MI的SIR与淹没面积百分比(r = 0.83;p <0.001)及海啸死亡人数(r = 0.77;p <0.005)显著相关,但与最大地震烈度无关(r = 0.43;p = 0.12)。总之,这些结果表明,这场毁灭性的海啸与灾难幸存者中致命性MI发病率的持续上升有关。

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