Reifman Jaques, Kumar Kamal, Wesensten Nancy J, Tountas Nikolaos A, Balkin Thomas J, Ramakrishnan Sridhar
Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD.
Air Traffic Organization, Federal Aviation Administration, Washington, DC.
Sleep. 2016 Dec 1;39(12):2157-2159. doi: 10.5665/sleep.6318.
Computational tools that predict the effects of daily sleep/wake amounts on neurobehavioral performance are critical components of fatigue management systems, allowing for the identification of periods during which individuals are at increased risk for performance errors. However, none of the existing computational tools is publicly available, and the commercially available tools do not account for the beneficial effects of caffeine on performance, limiting their practical utility. Here, we introduce Web, an open-access tool for predicting neurobehavioral performance, which accounts for the effects of sleep/wake schedules, time of day, and caffeine consumption, while incorporating the latest scientific findings in sleep restriction, sleep extension, and recovery sleep.
We combined our validated Unified Model of Performance and our validated caffeine model to form a single, integrated modeling framework instantiated as a Web-enabled tool. Web allows users to input daily sleep/wake schedules and caffeine consumption (dosage and time) to obtain group-average predictions of neurobehavioral performance based on psychomotor vigilance tasks. Web is accessible at: https://2b-alert-web.bhsai.org.
The Web tool allows users to obtain predictions for mean response time, mean reciprocal response time, and number of lapses. The graphing tool allows for simultaneous display of up to seven different sleep/wake and caffeine schedules. The schedules and corresponding predicted outputs can be saved as a Microsoft Excel file; the corresponding plots can be saved as an image file. The schedules and predictions are erased when the user logs off, thereby maintaining privacy and confidentiality.
The publicly accessible Web tool is available for operators, schedulers, and neurobehavioral scientists as well as the general public to determine the impact of any given sleep/wake schedule, caffeine consumption, and time of day on performance of a group of individuals. This evidence-based tool can be used as a decision aid to design effective work schedules, guide the design of future sleep restriction and caffeine studies, and increase public awareness of the effects of sleep amounts, time of day, and caffeine on alertness.
预测每日睡眠/清醒时长对神经行为表现影响的计算工具是疲劳管理系统的关键组成部分,有助于识别个体出现行为失误风险增加的时间段。然而,现有的计算工具均未公开,且商业可用工具未考虑咖啡因对表现的有益影响,限制了它们的实际效用。在此,我们推出了Web,这是一种用于预测神经行为表现的开放获取工具,它考虑了睡眠/清醒时间表、一天中的时间以及咖啡因摄入的影响,同时纳入了睡眠限制、睡眠延长和恢复性睡眠方面的最新科学发现。
我们将经过验证的统一表现模型和经过验证的咖啡因模型相结合,形成一个单一的综合建模框架,并实例化为一个基于网络的工具。Web允许用户输入每日睡眠/清醒时间表和咖啡因摄入量(剂量和时间),以基于心理运动警觉任务获得神经行为表现的群体平均预测。可通过以下网址访问Web:https://2b - alert - web.bhsai.org。
Web工具允许用户获得平均反应时间、平均倒数反应时间和失误次数的预测。绘图工具允许同时显示多达七种不同的睡眠/清醒和咖啡因时间表。这些时间表和相应的预测输出可以保存为Microsoft Excel文件;相应的图表可以保存为图像文件。当用户注销时,时间表和预测会被删除,从而维护隐私和保密性。
公开可用的Web工具可供操作员、调度员、神经行为科学家以及普通公众使用,以确定任何给定的睡眠/清醒时间表、咖啡因摄入量和一天中的时间对一组个体表现的影响。这个基于证据的工具可作为一种决策辅助工具,用于设计有效的工作时间表、指导未来睡眠限制和咖啡因研究的设计,并提高公众对睡眠时长、一天中的时间和咖啡因对警觉性影响的认识。