中毒性视神经病变后乙胺丁醇的再治疗

Re-Treatment With Ethambutol After Toxic Optic Neuropathy.

作者信息

Bouffard Marc A, Nathavitharana Ruvandhi R, Yassa David S, Torun Nurhan

机构信息

Department of Neurology (MAB, NT), Beth Israel Deaconess Medical Center, Boston, Massachusetts; Division of Infectious Disease (RRN, DY), Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts; and Division of Ophthalmology (NT), Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

出版信息

J Neuroophthalmol. 2017 Mar;37(1):40-42. doi: 10.1097/WNO.0000000000000445.

DOI:10.1097/WNO.0000000000000445

PMID:27636749

Abstract

There are no data in the literature regarding the safety of re-treatment with ethambutol for recurrent mycobacterial infection after prior ethambutol-induced optic neuropathy. We describe a patient who developed optic neuropathy attributed to ethambutol, recovered fully after drug withdrawal, and tolerated a 14-month long re-treatment 10 years later without developing recurrent optic neuropathy.

摘要

文献中没有关于既往乙胺丁醇诱发视神经病变后复发性分枝杆菌感染再次使用乙胺丁醇治疗安全性的数据。我们描述了一名患者，该患者出现了由乙胺丁醇引起的视神经病变，停药后完全康复，10年后耐受了长达14个月的再次治疗，且未出现复发性视神经病变。