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[毛果芸香碱鼻腔激发试验在血管运动性和息肉样鼻病中的应用]

[Carbachol nasal provocation test in vasomotor and polyposis rhinopathy].

作者信息

Latorre F, Fiorella R, Cassano P, Di Nicola V

出版信息

Acta Otorhinolaryngol Ital. 1989 Mar-Apr;9(2):119-29.

PMID:2763839
Abstract

A group of 117 subjects suffering from vasomotor rhinopathy (33 with nasal polyposis) were studied with the nasal provocation test with carbacholine in order to evaluate aspecific nasal reactivity. The results obtained by quantifying the variations in nasal secretions and rhinomanometric resistance after application of the test substance indicate the following: a marked hypersecretory response and obstruction in 80% of the vasomotor rhinitis cases; a more marked aspecific reactivity in perennial allergic rhinitis sufferers than in those with seasonal atopic rhinopathy; a lack of statistical significance between the group of those with atopic polyposis and those with a negative skin test. The authors conclude by confirming the usefulness of the test for aspecific reactivity in the diagnosis of vasomotor rhinopathy and propose its use for better screening those patients to undergo specific hyposensitivity therapy.

摘要

对117名患有血管运动性鼻炎的受试者(其中33名患有鼻息肉)进行了卡巴胆碱鼻激发试验,以评估非特异性鼻反应性。通过对应用测试物质后鼻分泌物变化和鼻阻力测量结果进行量化,得出以下结果:80%的血管运动性鼻炎病例出现明显的分泌亢进反应和阻塞;常年性变应性鼻炎患者的非特异性反应性比季节性特应性鼻病患者更明显;特应性息肉病组与皮肤试验阴性组之间无统计学意义。作者通过确认该试验对血管运动性鼻炎诊断中非特异性反应性的有用性得出结论,并建议将其用于更好地筛选那些接受特异性脱敏治疗的患者。

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Acta Otorhinolaryngol Ital. 1989 Mar-Apr;9(2):119-29.
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