胸部 CT 上的磨玻璃结节作为肺腺癌管理中的影像生物标志物。
Ground-glass nodules on chest CT as imaging biomarkers in the management of lung adenocarcinoma.
机构信息
Department of Radiology, Seoul National University College of Medicine, Institute of Radiation Medicine, Seoul National University Medical Research Center, Daehangno, Jongno-gu, Korea.
出版信息
AJR Am J Roentgenol. 2011 Mar;196(3):533-43. doi: 10.2214/AJR.10.5813.
OBJECTIVE
The purpose of this article is to review the clinical significance of ground-glass nodules (GGNs) in the management of lung adenocarcinoma.
CONCLUSION
GGNs can serve as imaging biomarkers that represent the bronchioloalveolar carcinoma component in adenocarcinoma on histology and indicate a better prognosis in patients with lung adenocarcinoma. The evolution of GGNs reflects the multistep progression of adenocarcinoma. Despite the high probability of malignancy of GGNs, the possibility of overdiagnosis should be considered in the management of GGNs.
目的
本文旨在综述磨玻璃结节（GGN）在肺腺癌诊治中的临床意义。
结论
GGN 可作为影像学生物标志物，代表腺癌组织学中的细支气管肺泡癌成分，并提示肺腺癌患者预后较好。GGN 的演变反映了腺癌的多步骤进展。尽管 GGN 的恶性可能性较高，但在 GGN 的处理中应考虑过度诊断的可能性。
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