VanDyck P, Chadband R, Chaudhary B, Stachura M E
Department of Medicine, Medical College of Georgia, Augusta.
Am J Med Sci. 1989 Aug;298(2):119-22. doi: 10.1097/00000441-198908000-00008.
The symptoms of hypothyroidism are protean and include apathy, somnolence, lethargy, personality change, and intellectual deterioration. Many of these symptoms may be related to hypothyroid-induced sleep disorders. Hypothyroidism is associated with abnormal ventilatory drive, abnormal sleep architecture, and sleep apnea. Central, obstructive, and mixed patterns of sleep apnea are commonly observed in hypothyroidism. A case of severe sleep apnea in a grossly myxedematous patient who improved dramatically following thyroid replacement alone is presented. Myxedema is a reversible cause of sleep apnea, and thyroid function testing should be considered in its diagnostic work-up.
甲状腺功能减退的症状多种多样，包括冷漠、嗜睡、慵懒、性格改变和智力衰退。这些症状中的许多可能与甲状腺功能减退引起的睡眠障碍有关。甲状腺功能减退与通气驱动异常、睡眠结构异常和睡眠呼吸暂停有关。睡眠呼吸暂停的中枢性、阻塞性和混合性模式在甲状腺功能减退中很常见。本文介绍了一例重度黏液性水肿患者的严重睡眠呼吸暂停病例，该患者仅在甲状腺替代治疗后就有显著改善。黏液性水肿是睡眠呼吸暂停的一个可逆原因，在其诊断检查中应考虑进行甲状腺功能测试。
