Trappe Hans-Joachim
Dtsch Med Wochenschr. 2016 Sep;141(19):1361-9. doi: 10.1055/s-0042-103177. Epub 2016 Sep 19.
Consciousness disorders may have many causes, mainly cardiac arrhythmias. The incidence of bradyarrhythmias (BA) in patients with acute coronary syndrome (ACS) is 0.3-18 % and caused by sinus node dysfunction (SND), high degree atrioventricular (AV) block or bundle branch blocks. SND are sinus bradycardia or sinus arrest. 1st degree AV-block occurs in 4-13 % of patients with ACS caused by rhythm disturbances in atrium, AV node, bundle of His or the Tawara system. 1st or 2nd degree AV block is seen very frequently within 24 hours after beginning of ACS and these arrhythmias are frequently transient and no more present after 72 hours. 3rd degree AV blocks are also frequently transient in pts with infero-posterior myocardial infarction (MI) and permanent in anterior MI patients. Left anterior fascicular block occurs in 5 % of ACS, left posterior fascicular block is observed less frequently (incidence < 0.5 %). Complete bundle branch block is present in 10-15 % of ACS patients and right bundle branch block is more often (2/3) present than left bundle branch block (1/3). In patients with BA atropine i. v. (1-3 mg) is helpful in 70-80 % of ACS patients and will lead to an increased heart rate. The need of pacemaker stimulation (PS) is different in patients with inferior (IMI) or anterior MI (AMI). Tachyarrhythmias are ventricular tachycardia, ventricular flutter or ventricular fibrillation in pts with ACS and it is necessary to terminate these arrhythmias as soon as possible by direct current cardioversion or defibrillation. Other causes of consciousness disorders are valvular heart diseases (aortic stenosis, hypertrophic obstructive cardiomyopathy), myxoma or ion-channel diseases (Brugada syndrome, long and short QT-syndromes). In all cases, a detailed cardiological evaluation is necessary in order to initiate a proper treatment.
意识障碍可能有多种原因,主要是心律失常。急性冠状动脉综合征(ACS)患者中缓慢性心律失常(BA)的发生率为0.3% - 18%,由窦房结功能障碍(SND)、高度房室(AV)传导阻滞或束支传导阻滞引起。SND包括窦性心动过缓或窦性停搏。一度AV传导阻滞发生在4% - 13%的ACS患者中,由心房、房室结、希氏束或房室束系统的节律紊乱引起。一度或二度AV传导阻滞在ACS开始后24小时内非常常见,这些心律失常通常是短暂的,72小时后不再出现。三度AV传导阻滞在急性下后壁心肌梗死(MI)患者中也常为短暂性,而在前壁MI患者中则为永久性。左前分支阻滞发生在5%的ACS患者中,左后分支阻滞较少见(发生率<0.5%)。完全性束支传导阻滞存在于10% - 15%的ACS患者中,右束支传导阻滞比左束支传导阻滞更常见(2/3)。对于BA患者,静脉注射阿托品(1 - 3毫克)对70% - 80%的ACS患者有帮助,会导致心率增加。下壁心肌梗死(IMI)或前壁心肌梗死(AMI)患者对起搏器刺激(PS)的需求不同。快速性心律失常在ACS患者中为室性心动过速、室性扑动或心室颤动,必须通过直流电复律或除颤尽快终止这些心律失常。意识障碍的其他原因是心脏瓣膜病(主动脉瓣狭窄、肥厚性梗阻性心肌病)、黏液瘤或离子通道疾病(Brugada综合征、长QT综合征和短QT综合征)。在所有情况下,都需要进行详细的心脏评估以便开始适当的治疗。