Rosenfeld L E
Yale University School of Medicine, New Haven, Connecticut.
Cardiol Clin. 1988 Feb;6(1):49-61.
Bradyarrhythmias and conduction disturbances are not infrequently observed in association with acute MI. The sinus node artery is supplied by the right coronary circulation only slightly more often than the left. As a result of concomitant vagotonia, however, sinus node dysfunction is more common with inferior infarction. This influence, as well as a predominantly right-sided circulation, also makes AV nodal block more frequent with such infarctions. Bradyarrhythmias due to sinus or AV nodal dysfunction often require only observation. If symptomatic, they are usually responsive to vagolytic or chronotropic drugs, but may necessitate pacemaker therapy often only on a temporary basis. The distal conduction system including the bundle branches is supplied mainly, but not exclusively, by the left anterior descending artery. Thus, acute bundle branch block is often associated with anterior MI. The indications for both temporary and permanent prophylactic pacing in this situation remain controversial. Several authors have made recommendations based on risk stratification. We would temporarily pace patients with anterior or indeterminate infarctions and new right or left bundle branch block, and probably those with bilateral bundle branch block of indeterminate age. All patients with new bilateral or alternating bundle branch block should be paced, regardless of infarct site. Permanent prophylactic pacing would appear indicated in patients exhibiting alternating bundle branch block or perhaps new right bundle branch block and left posterior hemiblock. In contrast to this group, the treatment of patients who develop sudden complete heart block, whether transient or permanent, is clear-cut. These patients require continuous (temporary followed without interruption by permanent) pacemaker therapy (Table 3).
缓慢性心律失常和传导障碍在急性心肌梗死(MI)时并不少见。窦房结动脉由右冠状动脉供血的情况仅略多于左冠状动脉。然而,由于伴随的迷走神经张力增高,窦房结功能障碍在下壁梗死时更为常见。这种影响以及主要为右侧的循环,也使得房室结阻滞在这类梗死时更为频繁。由窦房结或房室结功能障碍引起的缓慢性心律失常通常仅需观察。如果有症状,它们通常对抗迷走神经或变时性药物有反应,但可能常常仅需临时进行起搏器治疗。包括束支在内的远端传导系统主要(但并非唯一)由左前降支动脉供血。因此,急性束支阻滞常与前壁MI相关。在这种情况下,临时和永久性预防性起搏的指征仍存在争议。几位作者已根据风险分层提出了建议。我们会对发生前壁或梗死部位不明且出现新的右或左束支阻滞的患者,可能还有年龄不明的双侧束支阻滞患者进行临时起搏。所有新发双侧或交替性束支阻滞的患者,无论梗死部位如何,均应进行起搏。对于出现交替性束支阻滞或可能是新发右束支阻滞合并左后分支阻滞的患者,似乎有必要进行永久性预防性起搏。与这组患者不同,对于发生突然完全性心脏阻滞的患者,无论其为暂时性还是永久性,治疗方法是明确的。这些患者需要持续(先临时起搏,随后不间断地更换为永久性起搏)起搏器治疗(表3)。