Li Ruichao, Ye Lianwei, Zheng Zhiwei, Chan Edward Wai Chi, Chen Sheng
Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China.
State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Antimicrob Agents Chemother. 2016 Oct 21;60(11):6965-6968. doi: 10.1128/AAC.01749-16. Print 2016 Nov.
This report describes the first detection of a bla gene in a Vibrio parahaemolyticus strain isolated from a shrimp sample. The bla gene was carried on a novel Inc-type plasmid that was likely to have originated from aquatic organisms, as indicated by a comparison with other known genetic elements in the GenBank database. However, the plasmid contains resistance elements usually harbored by members of the family Enterobacteriaceae, suggesting that gene transfer events occurred and contributed to the formation of this multidrug resistance-encoding plasmid.
本报告描述了从一份虾样本中分离出的副溶血性弧菌菌株中首次检测到bla基因。bla基因携带在一种新型Inc型质粒上,通过与GenBank数据库中的其他已知遗传元件比较表明,该质粒可能起源于水生生物。然而,该质粒含有肠杆菌科成员通常携带的抗性元件,这表明发生了基因转移事件,并促成了这种多药抗性编码质粒的形成。