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Neopuff T型复苏器:设备设计会影响通气输送吗?

Neopuff T-piece resuscitator: does device design affect delivered ventilation?

作者信息

Hinder Murray, Jani Pranav, Priyadarshi Archana, McEwan Alistair, Tracy Mark

机构信息

Neonatal Intensive Care, Westmead Hospital, Westmead, New South Wales, Australia.

Faculty of Engineering and Information Technologies, BMET Institute, Sydney University, Sydney, New South Wales, Australia.

出版信息

Arch Dis Child Fetal Neonatal Ed. 2017 May;102(3):F220-F224. doi: 10.1136/archdischild-2016-311164. Epub 2016 Sep 19.

Abstract

BACKGROUND

The T-piece resuscitator (TPR) is in common use worldwide to deliver positive pressure ventilation during resuscitation of infants <10 kg. Ease of use, ability to provide positive end-expiratory pressure (PEEP), availability of devices inbuilt into resuscitaires and cheaper disposable options have increased its popularity as a first-line device for term infant resuscitation. Research into its ventilation performance is limited to preterm infant and animal studies. Efficacy of providing PEEP and the use of TPR during term infant resuscitation are not established.

AIM

The aim of this study is to determine if delivered ventilation with the Neopuff brand TPR varied with differing (preterm to term) test lung compliances (Crs) and set peak inspiratory pressures (PIP).

DESIGN

A single operator experienced in newborn resuscitation provided positive pressure ventilation in a randomised sequence to three different Crs models (0.5, 1 and 3 mL/cmHO) at three different set PIP (20, 30 and 40 cmHO). Set PEEP (5 cmHO), gas flow rate and inflation rate were the same for each sequence.

RESULTS

A total of 1087 inflations were analysed. The delivered mean PEEP was Crs dependent across set PIP range, rising from 4.9 to 8.2 cmHO. At set PIP 40 cmHO and Crs 3 mL/cmHO, the delivered mean PIP was significantly lower at 35.3 cmHO.

CONCLUSIONS

As Crs increases, the Neopuff TPR can produce clinically significant levels of auto-PEEP and thus may not be optimal for the resuscitation of term infants with healthy lungs.

摘要

背景

T形管复苏器(TPR)在全球范围内广泛用于对体重<10 kg的婴儿进行复苏时提供正压通气。其使用方便、能够提供呼气末正压(PEEP)、复苏器内置该设备以及有更便宜的一次性选择,这些因素使其作为足月儿复苏的一线设备更受欢迎。对其通气性能的研究仅限于早产儿和动物研究。在足月儿复苏期间提供PEEP的效果以及TPR的使用尚未确定。

目的

本研究的目的是确定使用Neopuff品牌的TPR进行通气时,所输送的通气量是否会因不同的(早产儿到足月儿)测试肺顺应性(Crs)和设定的吸气峰压(PIP)而有所不同。

设计

一名有新生儿复苏经验的单一操作人员以随机顺序对三种不同的Crs模型(0.5、1和3 mL/cmH₂O)在三种不同的设定PIP(20、30和40 cmH₂O)下提供正压通气。每个序列的设定PEEP(5 cmH₂O)、气体流速和充气速率相同。

结果

共分析了1087次充气。在所设定的PIP范围内,输送的平均PEEP取决于Crs,从4.9 cmH₂O上升到8.2 cmH₂O。在设定PIP为40 cmH₂O且Crs为3 mL/cmH₂O时,输送的平均PIP显著降低至35.3 cmH₂O。

结论

随着Crs增加,Neopuff TPR可产生具有临床意义的自动PEEP水平,因此对于肺部健康的足月儿复苏可能并非最佳选择。

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