Mekori Ehud, Halevy Liron, Ziv Shimrit Ilana, Moreno Ayelet, Enoch-Levy Adi, Weizman Abraham, Stein Daniel
a Safra Children's Hospital, The Chaim Sheba Medical Center , Tel Hashomer , Israel.
b Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv , Israel.
Int J Psychiatry Clin Pract. 2017 Mar;21(1):41-49. doi: 10.1080/13651501.2016.1229794. Epub 2016 Sep 20.
Research in eating disorders (EDs) suggests that outcome variables other than that of the ED per se, such as the presence of comorbid disorders and overall functioning at follow-up, may influence the ED condition at that time. We sought to assess the factors potentially predicting these different outcome variables.
Eighty-eight female adolescent in-patients with an ED were assessed on admission, discharge, and around one-year post-discharge using clinical interviews and self-rating questionnaires assessing ED and other relevant symptoms.
The mean body mass index (BMI) of patients with anorexia nervosa increased from admission to discharge and was maintained at follow-up. Twenty-eight patients were remitted at follow-up, whereas 48 and 12 patients had intermediate and poor ED-related outcome, respectively. Follow-up BMI was correlated with baseline BMI. Good ED-related outcome at follow-up according to accepted criteria was associated with more lifetime suicide attempts and more severe baseline ED symptomatology. Elevated psychiatric comorbidity at follow-up was associated with elevated baseline anxiety and with re-hospitalisation during the post-discharge follow-up period. Better academic/occupational functioning and social functioning at follow-up were associated with less lifetime suicide attempts, less re-hospitalisation and lower baseline anxiety.
In EDs, diverse factors may predict different outcome variables.
饮食失调（ED）方面的研究表明，除了饮食失调本身之外的结果变量，如共病障碍的存在以及随访时的整体功能状况，可能会影响当时的饮食失调状况。我们试图评估可能预测这些不同结果变量的因素。
对88名患有饮食失调的女性青少年住院患者在入院时、出院时以及出院后约一年进行评估，使用临床访谈和自评问卷来评估饮食失调及其他相关症状。
神经性厌食症患者的平均体重指数（BMI）从入院到出院有所增加，并在随访时保持稳定。28名患者在随访时康复，而分别有48名和12名患者的饮食失调相关结果处于中等和较差水平。随访时的BMI与基线BMI相关。根据公认标准，随访时良好的饮食失调相关结果与更多的终身自杀未遂次数以及更严重的基线饮食失调症状相关。随访时精神疾病共病率升高与基线焦虑水平升高以及出院后随访期间再次住院相关。随访时更好的学业/职业功能和社交功能与更少的终身自杀未遂次数、更少的再次住院以及更低的基线焦虑相关。
在饮食失调中，多种因素可能预测不同的结果变量。
