Zuo T T, Zheng R S, Zeng H M, Zhang S W, Chen W Q, He J
National Office for Cancer Prevention and Control, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhonghua Zhong Liu Za Zhi. 2016 Sep 23;38(9):703-8. doi: 10.3760/cma.j.issn.0253-3766.2016.09.013.
Incidence data retrieved from population-based cancer registration were used to analyze the esophageal cancer incidence and trend in China. The results can provide basic information for prevention and control of esophageal cancer.
Esophageal cancer incidence data in 2012 were retrieved from the National Central Cancer Registry, nationwide new esophageal cancer cases were estimated using age-specific rate by urban or rural and gender and national population in 2012. Esophageal cancer incidence data from 22 cancer registries were used to analyze the trend during 2000-2011.
The estimates of new cases of esophageal cancer were about 286.7 thousand in 2012 in China. The incidence rate was 21.17/10(5,) the age-standardized incidence rates by Chinese standard population and by world population were 14.73/10(5) and 14.93/10(5,) respectively, and the cumulative incidence rate was 1.91%.There was a decreasing trend of incidence rate of esophageal cancer in registration areas of China during 2000-2011 with an average annual percentage change (AAPC) of 0.9% (95%CI: -1.6% to -0.1%), no significant differences were observed in urban area and an increasing trend with AAPC of 1.3% (95%CI: 0.2% to 2.5%) in rural area. After age standardization, the incidence rate was significantly decreased, with AAPC of -4.0% (95%CI: -5.5% to -2.6%) overall, -3.8% (95%CI: -4.9% to -2.7%) in urban and -1.7% (95%CI: -3.0% to -0.4%) in rural areas.
Esophageal cancer is one of the most common cancers in China and is an emphasis for cancer control. After effective control of risk factors and development of esophageal cancer screening techniques in high-risk areas for years, esophageal cancer incidence appears to have a significant decreasing trend.
利用基于人群的癌症登记数据，分析中国食管癌的发病率及变化趋势，为食管癌防治提供基础信息。
从国家癌症中心获取2012年食管癌发病数据，采用2012年城乡、性别特异发病率及全国人口数估算全国新发食管癌病例数。利用22个癌症登记处的食管癌发病数据，分析2000 - 2011年的发病趋势。
2012年中国新发食管癌病例估计约28.67万例。发病率为21.17/10万，中国标准人口和世界人口年龄标化发病率分别为14.73/10万和14.93/10万，累积发病率为1.91%。2000 - 2011年中国癌症登记地区食管癌发病率呈下降趋势，平均年变化百分比（AAPC）为0.9%（95%CI：-1.6%至-0.1%），城市地区无显著差异，农村地区呈上升趋势，AAPC为1.3%（95%CI：0.2%至2.5%）。年龄标化后，发病率显著下降，总体AAPC为-4.0%（95%CI：-5.5%至-2.6%），城市为-3.8%（95%CI：-4.9%至-2.7%），农村为-1.7%（95%CI：-3.0%至-0.4%）。
食管癌是中国常见癌症之一，是癌症防控重点。多年来在高危地区有效控制危险因素并开展食管癌筛查技术后，食管癌发病率呈显著下降趋势。
