Zuo Tingting, Zheng Rongshou, Zeng Hongmei, Zhang Siwei, Chen Wanqing
National Cancer Center, National Office for Cancer Prevention and Control, Beijing 100021, China.
National Cancer Center, National Office for Cancer Prevention and Control, Beijing 100021, China; Email:
Zhonghua Zhong Liu Za Zhi. 2015 Sep;37(9):691-6.
The national population-based cancer registration data were used to analyze the liver cancer incidence and trend in China, in order to provide advise for making further strategy on liver cancer prevention and control.
Liver cancer data of 2011 were retrieved from the database of the National Cancer Registry. The incident cases of liver cancer were estimated using age-specific rate by urban or rural areas and gender according to the national population in 2011. Liver cancer incidence data from 22 cancer registries were used to analyze the incidence trend during 2000-2011.
The estimates of new cases of liver cancer were about 356 thousand in China in 2011. The incidence rate was 26.39/10(5,) and the age-standardized incidence rates by Chinese standard population and by world population were 19.48/10(5) and 19.10/10(5,) respectively.There was an increasing trend of incidence rate of liver cancer in China during 2000-2011 with an average annual percentage change(AAPC) of 1.0% (95%CI: 0.5%-1.4%), 1.2% (95%CI: 0.7%-1.8%)in urban areas and 1.1% (95%CI: 0.5%-1.8%) in rural areas. After age standardization, the incidence rate was significantly decreased, with an AAPC of -1.8% (95%CI: -2.4% to -1.2%), -1.6% (95%CI: -2.2% to -0.9%) in urban and -1.4% (95%CI: -2.5% to -0.3%) in rural areas.
Liver cancer is a common cancer in China. As changing in people's dietary habits and implementing neonatal HBV vaccination for years, the exposure to risk factors is reducing, and age-standardized incidence rate is decreasing. While cardinal number of population is big and aging population is growing rapidly in the country, trend of incidence rate is increasing, and the burden of liver cancer is still high in China.
利用全国基于人群的癌症登记数据，分析中国肝癌的发病情况及趋势，为制定进一步的肝癌防控策略提供建议。
从全国癌症登记数据库中检索2011年肝癌数据。根据2011年全国人口，采用按城乡和性别划分的年龄别发病率估算肝癌发病病例。利用22个癌症登记处的肝癌发病数据，分析2000 - 2011年期间的发病趋势。
2011年中国肝癌新发病例估计约为35.6万例。发病率为26.39/10万，中国标准人口和世界人口的年龄标准化发病率分别为19.48/10万和19.10/10万。2000 - 2011年中国肝癌发病率呈上升趋势，年均变化百分比（AAPC）为1.0%（95%CI：0.5% - 1.4%），城市地区为1.2%（95%CI：0.7% - 1.8%），农村地区为1.1%（95%CI：0.5% - 1.8%）。年龄标准化后，发病率显著下降，城市地区AAPC为 - 1.8%（95%CI： - 2.4%至 - 1.2%），农村地区为 - 1.4%（95%CI： - 2.5%至 - 0.3%）。
肝癌是中国常见的癌症。随着人们饮食习惯的改变和多年来实施新生儿乙肝疫苗接种，危险因素暴露减少，年龄标准化发病率下降。但由于中国人口基数大且老龄化人口快速增长，发病率仍呈上升趋势，肝癌负担依然较重。
