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从枣中分离出的两种新型C-葡萄糖基黄酮类化合物及其抗炎活性。

Two new C-glucosyl flavonoids from Ziziphus jujube and their anti-inflammatory activity.

作者信息

Fu Qiang, Ma Yu, Chen Jiang, Yuan Hai-Mei, Zheng Yu-Zhong

机构信息

a School of Pharmacy and Bioengineering , Chengdu University , Chengdu 610106 , China.

b School of Biology Sciences and Food Technology , Hanshan Normal University , Chaozhou 521041 , China.

出版信息

J Asian Nat Prod Res. 2017 May;19(5):462-467. doi: 10.1080/10286020.2016.1234458. Epub 2016 Sep 21.

DOI:10.1080/10286020.2016.1234458
PMID:27649580
Abstract

Two new C-glucosyl flavonoids 6''-O-feruloylspinosin and 6''-O-feruloyl-6'''-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed moderate inhibitory effects against COX-1 and COX-2 enzymes.

摘要

从鼠李科植物酸枣种子中分离出两种新的C-葡萄糖基黄酮类化合物6''-O-阿魏酰斯皮诺素和6''-O-阿魏酰-6'''-对羟基苯甲酰斯皮诺素,以及五种已知化合物。基于化学和光谱证据阐明了它们的结构。化合物1-7对COX-1和COX-2酶表现出中等抑制作用。

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