用于测量动脉僵硬度的压平式眼压计脉搏波分析
Pulse Wave Analysis by Applanation Tonometry for the Measurement of Arterial Stiffness.
作者信息
Doupis John, Papanas Nikolaos, Cohen Alison, McFarlan Lyndsay, Horton Edward
机构信息
Joslin Diabetes Centre, Harvard Medical School, Boston, MA, USA.
Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
出版信息
Open Cardiovasc Med J. 2016 Aug 31;10:188-95. doi: 10.2174/1874192401610010188. eCollection 2016.
The aim of our study was to investigate the association between pulse wave velocity (PWV) and pulse wave analysis (PWA)-derived measurements for the evaluation of arterial stiffness. A total of 20 (7 male and 13 female) healthy, non-smoking individuals, with mean age 31 ± 12years were included. PWV and PWA measurements were performed using a SphygmoCor apparatus (Atcor Medical Blood Pressure Analysis System, Sydney Australia). PWV significantly correlated with all central aortic haemodynamic parameters, especially with pulse pressure (PP) (p < 0.0001), augmentation index corrected for 75 pulses/min (AI75) (p = 0.035) and augmentation pressure (AP) (p = 0.005). Male subjects presented significantly higher PWV compared with females (p = 0.03), while there were no differences in PP, AP and AI75. In conclusion, PWA is strongly correlated with PWV as a method for the evaluation of arterial stiffness.
我们研究的目的是调查脉搏波速度（PWV）与基于脉搏波分析（PWA）得出的测量值之间的关联，以评估动脉僵硬度。共纳入了20名（7名男性和13名女性）健康、不吸烟的个体，平均年龄为31±12岁。使用SphygmoCor仪器（澳大利亚悉尼Atcor Medical血压分析系统）进行PWV和PWA测量。PWV与所有中心主动脉血流动力学参数显著相关，尤其是与脉压（PP）（p<0.0001）、校正为75次/分钟的增强指数（AI75）（p = 0.035）和增强压力（AP）（p = 0.005）。男性受试者的PWV显著高于女性（p = 0.03），而PP、AP和AI75没有差异。总之，作为评估动脉僵硬度的一种方法，PWA与PWV密切相关。
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