这是由小肠细菌过度生长引起的肠道相关皮肤病-关节炎综合征吗？
Is it bowel-associated dermatosis-arthritis syndrome induced by small intestinal bacteria overgrowth?
作者信息
Zhao Hongjun, Zhao Lijuan, Shi Wei, Luo Hui, Duan Liping, You Yunhui, Li Yisha, Zuo Xiaoxia
机构信息
Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan Province 410008 People's Republic of China.
Departments of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008 People's Republic of China.
出版信息
Springerplus. 2016 Sep 13;5(1):1551. doi: 10.1186/s40064-016-3236-8. eCollection 2016.
INTRODUCTION
Bowel-associated dermatosis-arthritis syndrome is rare systemic diseases characterized by a prodrome of fever, chills, and influenza-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias. It is reported to be occurred in Intestinal bypass surgery and inflammatory bowel disease.
CASE DESCRIPTION
Herein, we described a 29-years-old man with Bowel-associated dermatosis-arthritis syndrome. He had no history of gastrointestinal surgery and inflammatory bowel disease. Distribution of the gut bacterial flora showed small intestinal bacterial overgrowth.
DISCUSSION AND EVALUATION
It is rarely form as Non-intestinal bypass road and non-inflammatory bowel disease was induced by small intestinal bacteria overgrowth.
CONCLUSIONS
We concluded that Immuno-inflammatory response to overgrowth of intestinal bacterial antigen induce the clinical symptoms of bowel-associated dermatosis-arthritis syndrome.
引言
肠道相关皮肤病-关节炎综合征是一种罕见的全身性疾病，其特征为先兆症状为发热、寒战和流感样症状，随后出现皮肤疹、肌痛和多关节痛。据报道，它发生于肠道旁路手术和炎症性肠病。
病例描述
在此，我们描述了一名患有肠道相关皮肤病-关节炎综合征的29岁男性。他没有胃肠道手术和炎症性肠病的病史。肠道细菌菌群分布显示小肠细菌过度生长。
讨论与评估
很少有非肠道旁路途径且非炎症性肠病由小肠细菌过度生长诱发的情况。
结论
我们得出结论，对肠道细菌抗原过度生长的免疫炎症反应诱发了肠道相关皮肤病-关节炎综合征的临床症状。
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