Karamat Muhammad Irfan, Darvish-Molla Sahar, Santos-Diaz Alejandro
Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, ON, Canada.
McMaster School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada; Imaging Research Centre, St. Joseph's Healthcare, Hamilton, ON, Canada.
Crit Rev Biomed Eng. 2016;44(1-2):73-89. doi: 10.1615/CritRevBiomedEng.2016016365.
The desire to achieve clinical ultra-high magnetic resonance imaging (MRI) systems stems from the fact that higher field strength leads to higher signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and spatial resolution. During last few years 7T MRI systems have become a quasi standard for ultra-high field MRI (UhFMRI) systems. This review presents a detailed account of opportunities and challenges associated with a clinical 7T MRI system for cranial and extracranial imaging. As with all of the previous transitions to higher field strengths, the switch from high to UhFMRI is not easy. The engineering and scientific community have to overcome challenges like magnetic field inhomogeneity, patient safety and comfort issues, and cost and related problems in order to achieve a clinically viable UhFMRI system. In addition, a large number of clinical studies are still required to show the improvements in quality of diagnostics that would come with 7T MRI, in order to bring such a research tool to the clinic.
实现临床超高场磁共振成像(MRI)系统的愿望源于这样一个事实,即更高的场强会带来更高的信噪比(SNR)、对比噪声比(CNR)和空间分辨率。在过去几年中,7T MRI系统已成为超高场MRI(UhFMRI)系统的一种准标准。本综述详细阐述了临床7T MRI系统用于颅脑和颅外成像所带来的机遇与挑战。与以往向更高场强的所有转变一样,从高场向UhFMRI的转变并非易事。工程和科学界必须克服诸如磁场不均匀性、患者安全与舒适度问题以及成本和相关问题等挑战,以实现临床上可行的UhFMRI系统。此外,仍需要大量临床研究来证明7T MRI所带来的诊断质量的提升,以便将这样一种研究工具引入临床。