乳清蛋白补充剂对进行抗阻训练的老年人的影响：系统评价与荟萃分析
Effects of whey protein supplement in the elderly submitted to resistance training: systematic review and meta-analysis.
作者信息
Colonetti Tamy, Grande Antonio Jose, Milton Karen, Foster Charlie, Alexandre Maria Cecilia Manenti, Uggioni Maria Laura Rodrigues, Rosa Maria Inês da
机构信息
a Graduate Program in Health Sciences, Laboratory of Epidemiology , Universidade do Extremo Sul Catarinense , Criciuma , Brazil.
b Laboratory of Evidence-based Practice , Universidade do Extremo Sul Catarinense , Criciuma , Brazil.
出版信息
Int J Food Sci Nutr. 2017 May;68(3):257-264. doi: 10.1080/09637486.2016.1232702. Epub 2016 Sep 21.
AIM
We performed a systematic review to map the evidence and analyze the effect of whey protein supplementation in the elderly submitted to resistance training.
METHODS
A comprehensive search on Medline, LILACS, EMBASE, and the Cochrane Library for relevant publications was conducted until August 2015. The terms used in the search were: "Resistance training"; "Whey protein"; "Elderly".
RESULTS
A total of 632 studies were screened. Five studies were included composing a sample of 391 patients. The supplement whey protein was associated with higher total protein ingestion 9.40 (95% CI: 4.03-14.78), and with an average change in plasma leucine concentration. The supplementation was also associated with increased mixed muscle protein synthesis 1.26 (95% CI: 0.46-2.07) compared to the control group.
CONCLUSION
We observed an increase in total protein intake, resulting in increased concentration of leucine and mixed muscle protein fractional synthesis rate.
目的
我们进行了一项系统评价，以梳理证据并分析补充乳清蛋白对进行抗阻训练的老年人的影响。
方法
截至2015年8月，在Medline、LILACS、EMBASE和考克兰图书馆对相关出版物进行了全面检索。检索使用的术语为：“抗阻训练”；“乳清蛋白”；“老年人”。
结果
共筛选出632项研究。纳入了5项研究，构成了一个391名患者的样本。补充乳清蛋白与更高的总蛋白摄入量9.40（95%可信区间：4.03 - 14.78）相关，并且与血浆亮氨酸浓度的平均变化相关。与对照组相比，补充乳清蛋白还与混合肌肉蛋白合成增加1.26（95%可信区间：0.46 - 2.07）相关。
结论
我们观察到总蛋白摄入量增加，导致亮氨酸浓度升高和混合肌肉蛋白分数合成率增加。
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