Hayashi M, Yablonski M E, Boxrud C, Fong N, Berger C, Jovanovic L J
Department of Ophthalmology, Cornell University Medical College, New York, NY 10021.
Br J Ophthalmol. 1989 Aug;73(8):621-3. doi: 10.1136/bjo.73.8.621.
The rate of aqueous humour formation was measured by fluorophotometry in 34 insulin-dependent diabetic patients and 12 non-diabetic controls to determine whether or not aqueous flow in diabetics differed from that of normal controls, and whether or not aqueous flow among diabetics was correlated with the stage of retinopathy. Diabetic patients were divided into three groups based on the degree of retinopathy; group I without retinopathy, group II with minimal to moderate non-proliferative retinopathy, and group III with proliferative retinopathy. Aqueous flow (mean, SD) in diabetic patients was: 1.55 (0.32) microliter/min in group I, 1.51 (0.47) microliter/min in group II, and 1.26 (0.39) microliter/min in group III. No statistically significant difference was found among these three diabetic groups. Aqueous flow in the non-diabetic controls was 2.18 (0.40) microliter/min, and this was statistically significantly greater than in each of the diabetic groups. Intraocular pressure, age, duration of diabetes, haemoglobin A1C, and blood glucose levels had no significant effect on aqueous flow in diabetic patients.
通过荧光光度法测量了34名胰岛素依赖型糖尿病患者和12名非糖尿病对照者的房水生成速率，以确定糖尿病患者的房水流动是否与正常对照者不同，以及糖尿病患者之间的房水流动是否与视网膜病变阶段相关。根据视网膜病变程度将糖尿病患者分为三组：I组无视网膜病变，II组有轻度至中度非增殖性视网膜病变，III组有增殖性视网膜病变。糖尿病患者的房水流动（平均值，标准差）为：I组1.55（0.32）微升/分钟，II组1.51（0.47）微升/分钟，III组1.26（0.39）微升/分钟。这三个糖尿病组之间未发现统计学上的显著差异。非糖尿病对照者的房水流动为2.18（0.40）微升/分钟，这在统计学上显著高于每个糖尿病组。眼压、年龄、糖尿病病程、糖化血红蛋白和血糖水平对糖尿病患者的房水流动没有显著影响。
