Talbot R W, Ritchie J K, Northover J M
Department of Surgery, St. Mark's Hospital, London, UK.
Br J Surg. 1989 Jul;76(7):738-9. doi: 10.1002/bjs.1800760731.
Conservative proctocolectomy was performed for ulcerative colitis in 19 patients, Crohn's disease in three and familial adenomatous polyposis in one. Healing was uncomplicated in only three patients (13 per cent). Eleven developed an anal discharge and nine an infected pelvic haematoma despite peranal drainage. Fourteen patients developed pelvic sepsis and, despite surgical curettage in 11, none healed. Six of these patients have had the anal sphincter divided, with healing in only one, and the anal canal has been excised in two. Eleven patients have ultimately healed at a median time of 28 months and eight have persistent sepsis after a median period of 45 months. Two patients with sepsis have had a successful ileoanal anastomosis. Conservative proctocolectomy cannot be recommended as a definitive operation for ulcerative colitis even though it may permit a subsequent restorative procedure.
对19例溃疡性结肠炎、3例克罗恩病和1例家族性腺瘤性息肉病患者实施了保留性直肠结肠切除术。仅3例患者(13%)愈合过程顺利。11例出现肛门排出物,9例尽管进行了肛周引流仍发生感染性盆腔血肿。14例患者发生盆腔脓毒症,尽管11例进行了手术刮除,但均未愈合。其中6例患者进行了肛门括约肌切开术,仅1例愈合,2例切除了肛管。11例患者最终愈合,中位时间为28个月,8例在中位45个月后仍有持续性脓毒症。2例脓毒症患者进行回肠肛管吻合术获得成功。保留性直肠结肠切除术不能作为溃疡性结肠炎的确定性手术推荐,尽管它可能允许后续的修复性手术。