• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

二氧化锆种植体钻的生物学评价

Biological Evaluation of Implant Drill Made from Zirconium Dioxide.

作者信息

Akiba Yosuke, Eguchi Kaori, Akiba Nami, Uoshima Katsumi

机构信息

Division of Bio-prosthodontics, Department of Oral Health Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

出版信息

Clin Implant Dent Relat Res. 2017 Apr;19(2):306-315. doi: 10.1111/cid.12452. Epub 2016 Sep 22.

DOI:10.1111/cid.12452
PMID:27658993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5396264/
Abstract

PURPOSE

Zirconia is a good candidate material in the dental field. In this study, we evaluated biological responses against a zirconia drill using a bone cavity healing model.

MATERIALS AND METHODS

Zirconia drills, stainless steel drills, and the drilled bone surface were observed by scanning electron microscopy (SEM), before and after cavity preparation. For the bone cavity healing model, the upper first and second molars of Wistar rats were extracted. After 4 weeks, cavities were prepared with zirconia drills on the left side. As a control, a stainless steel drill was used on the right side. At 3, 7, and 14 days after surgery, micro-CT images were taken. Samples were prepared for histological staining.

RESULTS

SEM images revealed that zirconia drills maintained sharpness even after 30 drilling procedures. The bone surface was smoother with the zirconia drill. Micro-CT images showed faster and earlier bone healing in the zirconia drill cavity. On H-E staining, at 7 days, the zirconia drill defect had a smaller blank lacunae area. At 14 days, the zirconia drill defect was filled with newly formed bone.

CONCLUSIONS

The zirconia drill induces less damage during cavity preparation and is advantageous for bone healing. (197 words).

摘要

目的

氧化锆是牙科领域一种理想的候选材料。在本研究中，我们使用骨腔愈合模型评估了针对氧化锆钻的生物学反应。

材料与方法

在制备洞腔前后，通过扫描电子显微镜（SEM）观察氧化锆钻、不锈钢钻以及钻后的骨表面。对于骨腔愈合模型，拔除Wistar大鼠的上颌第一和第二磨牙。4周后，在左侧用氧化锆钻制备洞腔。作为对照，右侧使用不锈钢钻。术后3天、7天和14天拍摄微型CT图像。制备样本进行组织学染色。

结果

SEM图像显示，即使经过30次钻孔操作后，氧化锆钻仍保持锋利。使用氧化锆钻时骨表面更光滑。微型CT图像显示氧化锆钻洞腔的骨愈合更快且更早。在苏木精-伊红（H-E）染色中，7天时，氧化锆钻造成的缺损空白腔隙面积更小。14天时，氧化锆钻造成的缺损被新形成的骨填充。

结论

氧化锆钻在制备洞腔过程中造成的损伤较小，有利于骨愈合。（197字）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/d83f8a940ba0/CID-19-306-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/8715eb9109ef/CID-19-306-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/3607f7909604/CID-19-306-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/f3c3bb6aa5c4/CID-19-306-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/98ba59592f29/CID-19-306-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/5aca3675e625/CID-19-306-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/bbe7bf01294d/CID-19-306-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/c997a188ffc6/CID-19-306-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/d83f8a940ba0/CID-19-306-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/8715eb9109ef/CID-19-306-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/3607f7909604/CID-19-306-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/f3c3bb6aa5c4/CID-19-306-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/98ba59592f29/CID-19-306-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/5aca3675e625/CID-19-306-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/bbe7bf01294d/CID-19-306-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/c997a188ffc6/CID-19-306-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7461/5396264/d83f8a940ba0/CID-19-306-g008.jpg

相似文献

1
Biological Evaluation of Implant Drill Made from Zirconium Dioxide.二氧化锆种植体钻的生物学评价
Clin Implant Dent Relat Res. 2017 Apr;19(2):306-315. doi: 10.1111/cid.12452. Epub 2016 Sep 22.
2
Comparison of the physical, thermal, and biological effects on implant bone site when using either zirconia or stainless-steel drill for implant bone site preparation.比较使用氧化锆或不锈钢钻头制备种植体骨位时对种植体骨位的物理、热和生物学影响。
J Formos Med Assoc. 2024 Sep;123(9):954-960. doi: 10.1016/j.jfma.2024.01.011. Epub 2024 Jan 20.
3
Thermal changes and drill wear in bovine bone during implant site preparation. A comparative in vitro study: twisted stainless steel and ceramic drills.在种植体预备过程中牛骨的热变化和钻头磨损。一项比较性的体外研究：扭曲不锈钢和陶瓷钻头。
Clin Oral Implants Res. 2012 Aug;23(8):963-9. doi: 10.1111/j.1600-0501.2011.02248.x. Epub 2011 Aug 2.
4
Influence of the drill material and method of cooling on the development of intrabony temperature during preparation of the site of an implant.种植体植入部位预备过程中，钻针材料及冷却方法对骨内温度升高的影响。
Br J Oral Maxillofac Surg. 2013 Jan;51(1):74-8. doi: 10.1016/j.bjoms.2012.02.003. Epub 2012 Mar 13.
5
The influence of drill wear on cutting efficiency and heat production during osteotomy preparation for dental implants: a study of drill durability.钻头磨损对牙种植体截骨术准备过程中切削效率和产热的影响：一项关于钻头耐用性的研究
Int J Oral Maxillofac Implants. 2004 May-Jun;19(3):335-49.
6
Infrared thermographic evaluation of temperature modifications induced during implant site preparation with cylindrical versus conical drills.使用圆柱形与圆锥形钻头制备种植窝时产生的温度变化的红外热成像评估。
Clin Implant Dent Relat Res. 2011 Dec;13(4):319-23. doi: 10.1111/j.1708-8208.2009.00209.x. Epub 2009 Aug 3.
7
Osseointegration of zirconia and titanium dental implants: a histological and histomorphometrical study in the maxilla of pigs.氧化锆和钛牙科种植体的骨整合：猪上颌骨的组织学和组织形态计量学研究。
Clin Oral Implants Res. 2009 Nov;20(11):1247-53. doi: 10.1111/j.1600-0501.2009.01734.x. Epub 2009 Jun 15.
8
Osseointegration of zirconia implants: an SEM observation of the bone-implant interface.氧化锆种植体的骨结合：骨-种植体界面的扫描电子显微镜观察
Head Face Med. 2008 Nov 6;4:25. doi: 10.1186/1746-160X-4-25.
9
Infrared Thermographic Evaluation of Temperature Modifications Induced during Implant Site Preparation with Steel vs. Zirconia Implant Drill.使用不锈钢与氧化锆种植体钻进行种植体植入部位预备时温度变化的红外热成像评估
J Clin Med. 2020 Jan 5;9(1):148. doi: 10.3390/jcm9010148.
10
Biomechanical and histological behavior of zirconia implants: an experiment in the rat.氧化锆种植体的生物力学和组织学行为：大鼠实验
Clin Oral Implants Res. 2009 Apr;20(4):333-9. doi: 10.1111/j.1600-0501.2008.01656.x.

引用本文的文献

1
Steel drills versus zirconia drills on heat generation at the surgical site of dental implants: A systematic review and meta-analysis.牙科种植体手术部位使用钢钻与氧化锆钻产生热量的比较：一项系统评价和荟萃分析。
Saudi Dent J. 2024 Jan;36(1):1-10. doi: 10.1016/j.sdentj.2023.09.001. Epub 2023 Sep 7.
2
Effects of novel non-thermal atmospheric plasma treatment of titanium on physical and biological improvements and in vivo osseointegration in rats.新型非热常压等离子体处理钛对大鼠物理和生物学性能改善及体内骨整合的影响。
Sci Rep. 2020 Jun 30;10(1):10637. doi: 10.1038/s41598-020-67678-z.
3
Infrared Thermographic Evaluation of Temperature Modifications Induced during Implant Site Preparation with Steel vs. Zirconia Implant Drill.

本文引用的文献

1
Osteoblasts of calvaria induce higher numbers of osteoclasts than osteoblasts from long bone.颅盖骨的成骨细胞比长骨的成骨细胞诱导产生更多的破骨细胞。
Bone. 2016 May;86:10-21. doi: 10.1016/j.bone.2016.02.010. Epub 2016 Feb 24.
2
Cell-based bone regeneration for alveolar ridge augmentation--cell source, endogenous cell recruitment and immunomodulatory function.用于牙槽嵴增高的基于细胞的骨再生——细胞来源、内源性细胞募集及免疫调节功能
J Prosthodont Res. 2015 Apr;59(2):96-112. doi: 10.1016/j.jpor.2015.02.001. Epub 2015 Mar 4.
3
Thermal effects of a combined irrigation method during implant site drilling. A standardized in vitro study using a bovine rib model.
使用不锈钢与氧化锆种植体钻进行种植体植入部位预备时温度变化的红外热成像评估
J Clin Med. 2020 Jan 5;9(1):148. doi: 10.3390/jcm9010148.
种植位点钻孔过程中联合冲洗方法的热效应。一项使用牛肋骨模型的标准化体外研究。
Clin Oral Implants Res. 2014 Jun;25(6):665-74. doi: 10.1111/clr.12032. Epub 2012 Sep 26.
4
Influence of the drill material and method of cooling on the development of intrabony temperature during preparation of the site of an implant.种植体植入部位预备过程中，钻针材料及冷却方法对骨内温度升高的影响。
Br J Oral Maxillofac Surg. 2013 Jan;51(1):74-8. doi: 10.1016/j.bjoms.2012.02.003. Epub 2012 Mar 13.
5
Thermal changes and drill wear in bovine bone during implant site preparation. A comparative in vitro study: twisted stainless steel and ceramic drills.在种植体预备过程中牛骨的热变化和钻头磨损。一项比较性的体外研究：扭曲不锈钢和陶瓷钻头。
Clin Oral Implants Res. 2012 Aug;23(8):963-9. doi: 10.1111/j.1600-0501.2011.02248.x. Epub 2011 Aug 2.
6
Surface-modified zirconia implants: tissue response in rabbits.表面改性氧化锆种植体：兔体内的组织反应
Clin Oral Implants Res. 2009 Aug;20(8):844-50. doi: 10.1111/j.1600-0501.2009.01727.x.
7
Osteoclast heterogeneity: lessons from osteopetrosis and inflammatory conditions.破骨细胞异质性：来自骨质石化症和炎症性疾病的启示
Biochim Biophys Acta. 2009 Aug;1792(8):757-65. doi: 10.1016/j.bbadis.2009.05.004. Epub 2009 May 22.
8
Influence of heat stress to matrix on bone formation.热应激对基质在骨形成方面的影响。
Clin Oral Implants Res. 2009 Aug;20(8):782-90. doi: 10.1111/j.1600-0501.2008.01654.x.
9
Osseointegration of zirconia implants compared with titanium: an in vivo study.氧化锆种植体与钛种植体的骨结合：一项体内研究。
Head Face Med. 2008 Dec 11;4:30. doi: 10.1186/1746-160X-4-30.
10
Stem cell renewal and contraction of the tunica media caused by a damaged blood vessel following a thick needle stab.厚针穿刺后受损血管引起的干细胞更新和中膜收缩。
Eur J Drug Metab Pharmacokinet. 2007 Jul-Sep;32(3):149-62. doi: 10.1007/BF03190477.