Verweij Marcel, Lambach Philipp, Ortiz Justin R, Reis Andreas
Section Communication, Philosophy and Technology, Department of Social Sciences, Wageningen University, Wageningen, Netherlands.
Initiative for Vaccine Research, World Health Organization, Geneva, Switzerland.
Lancet Infect Dis. 2016 Dec;16(12):e310-e314. doi: 10.1016/S1473-3099(16)30349-8. Epub 2016 Sep 20.
There has been increased interest in the potential of maternal immunisation to protect maternal, fetal, and infant health. Maternal tetanus vaccination is part of routine antenatal care and immunisation campaigns in many countries, and it has played an important part in the reduction of maternal and neonatal tetanus. Additional vaccines that have been recommended for routine maternal immunisation include those for influenza and pertussis, and other vaccines are being developed. Maternal immunisation is controversial since regulators, professionals, and the public are often reluctant to accept pharmaceutical interventions during pregnancy. So far, little attention has been given to the ethics of vaccination during pregnancy. In this Personal View we argue that maternal immunisation should be offered in response to concrete, severe risks of disease for mother and child, and we explain how this requirement of serious risk can be used to guide ethical decision-making about maternal immunisation.
人们对母体免疫在保护母亲、胎儿和婴儿健康方面的潜力越来越感兴趣。在许多国家，产妇破伤风疫苗接种是常规产前护理和免疫运动的一部分，并且在减少产妇和新生儿破伤风方面发挥了重要作用。已建议用于常规母体免疫的其他疫苗包括流感疫苗和百日咳疫苗，并且正在研发其他疫苗。母体免疫存在争议，因为监管机构、专业人员和公众通常不愿意在怀孕期间接受药物干预。到目前为止，很少有人关注怀孕期间疫苗接种的伦理问题。在这篇个人观点文章中，我们认为应针对母亲和儿童面临的具体、严重疾病风险提供母体免疫，并且我们解释了如何利用这种严重风险要求来指导关于母体免疫的伦理决策。
