Linking impaired skin barrier function to esophageal allergic inflammation via IL-33.
作者信息
Travers Jared, Rochman Mark, Miracle Cora E, Cohen Jared P, Rothenberg Marc E
机构信息
Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
出版信息
J Allergy Clin Immunol. 2016 Nov;138(5):1381-1383. doi: 10.1016/j.jaci.2016.09.001. Epub 2016 Sep 21.
Abstract
摘要
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本文引用的文献
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Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice.变应性皮肤致敏通过 IL-33-嗜碱性粒细胞轴促进小鼠嗜酸性食管炎。
J Allergy Clin Immunol. 2016 Nov;138(5):1367-1380.e5. doi: 10.1016/j.jaci.2016.02.034. Epub 2016 Apr 19.
2
Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment.嗜酸性粒细胞性食管炎相关的钙蛋白酶14是一种由白细胞介素-13诱导的蛋白酶，可介导食管上皮屏障损伤。
JCI Insight. 2016 Apr;1(4):e86355. doi: 10.1172/jci.insight.86355.
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IL-33 in T Cell Differentiation, Function, and Immune Homeostasis.白细胞介素-33 在 T 细胞分化、功能和免疫稳态中的作用。
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Mechanisms of Disease of Eosinophilic Esophagitis.嗜酸性粒细胞性食管炎的发病机制
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Clin Exp Allergy. 2016 Mar;46(3):479-90. doi: 10.1111/cea.12683.
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Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation.活性嗜酸性粒细胞性食管炎的特征是上皮屏障缺陷和嗜酸性粒细胞细胞外陷阱的形成。
Allergy. 2015 Apr;70(4):443-52. doi: 10.1111/all.12570. Epub 2015 Jan 26.
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GWAS identifies four novel eosinophilic esophagitis loci.全基因组关联研究确定了四个新的嗜酸性粒细胞性食管炎基因座。
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The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders.白细胞介素-33/白细胞介素-1受体样蛋白1轴在过敏性疾病中肥大细胞和嗜碱性粒细胞活化中的作用。
Mol Immunol. 2015 Jan;63(1):80-5. doi: 10.1016/j.molimm.2014.06.018. Epub 2014 Jul 10.
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Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.嗜酸性粒细胞性食管炎的全基因组关联分析为这种过敏性疾病的组织特异性提供了见解。
Nat Genet. 2014 Aug;46(8):895-900. doi: 10.1038/ng.3033. Epub 2014 Jul 13.
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