Na Ling, Pan Qiang, Xie Dawei, Kurichi Jibby E, Streim Joel E, Bogner Hillary R, Saliba Debra, Hennessy Sean
Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(∗).
Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(†).
PM R. 2017 May;9(5):433-443. doi: 10.1016/j.pmrj.2016.09.008. Epub 2016 Sep 21.
Activity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been studied.
To examine the independent association of activity limitation stages with risk of hospitalization within a year among Medicare beneficiaries aged 65 years and older.
Cohort study.
Community.
A total of 9447 community-dwelling elderly Medicare beneficiaries from the Medicare Current Beneficiary Survey for years 2005-2009.
Stages were derived for ADLs and IADLs separately. Associations of stages with time to first hospitalization and time to recurrent hospitalizations within a year were assessed with Cox proportional hazards models, with which we accounted for baseline sociodemographics, smoking status, comorbidities, and the year of survey entry.
Time to first hospitalization and time to recurrent hospitalizations within 1 year.
The adjusted risk of first hospitalization increased with greater activity limitation stages (except stage III). The hazard ratios (95% confidence intervals) for ADL stages I-IV compared with stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2.06 (1.61-2.63), respectively. The pattern for IADL stages was similar. For recurrent hospitalizations, activity limitation stages were associated with the risk of the first hospitalization but not with subsequent hospitalizations.
Activity limitation stages are associated with the risk of first hospitalization in the subsequent year among elderly Medicare beneficiaries. Stages capture clinically interpretable profiles of ADL and IADL functionality and describe preserved functions and activity limitation in an aggregated measure. Stage can inform interventions to ameliorate disability and thus reduce the risk of a subsequent hospitalization in this population.
IV.
基于日常生活活动(ADL)和工具性日常生活活动(IADL)的活动受限阶段与老年医疗保险受益人的3年死亡率相关,但它们与该人群住院风险的关联尚未得到研究。
研究65岁及以上医疗保险受益人中活动受限阶段与1年内住院风险的独立关联。
队列研究。
社区。
2005 - 2009年医疗保险当前受益人调查中的9447名社区居住的老年医疗保险受益人。
分别得出ADL和IADL的阶段。使用Cox比例风险模型评估各阶段与首次住院时间和1年内再次住院时间的关联,该模型考虑了基线社会人口统计学、吸烟状况、合并症以及调查入组年份。
首次住院时间和1年内再次住院时间。
除III期外,首次住院的校正风险随活动受限阶段增加而升高。与0期(无限制)相比,ADL I - IV期的风险比(95%置信区间)分别为1.49(1.36 - 1.63)、1.61(1.44 - 1.80)、1.54(1.35 - 1.76)和2.06(1.61 - 2.63)。IADL阶段的模式相似。对于再次住院,活动受限阶段与首次住院风险相关,但与后续住院无关。
活动受限阶段与老年医疗保险受益人次年首次住院风险相关。这些阶段反映了ADL和IADL功能的临床可解释特征,并以综合指标描述了保留功能和活动受限情况。该阶段可为改善残疾的干预措施提供参考,从而降低该人群后续住院的风险。
IV级。