Togo A H, Diop A, Dubourg G, Nguyen T T, Andrieu C, Caputo A, Couderc C, Fournier P-E, Maraninchi M, Valero R, Raoult D, Million M
Aix Marseille Université, URMITE, Institut Hospitalier Universitaire Méditerranée-Infection, UM63, CNRS7278, IRD198, INSERM1095, France.
Aix Marseille Université, NORT "Nutrition, Obesity and Risk of Thrombosis", INSERM1062, INRA1260, F-13385 Marseille, France; APHM, CHU Hôpital de la Conception, Service Nutrition, Maladies Métaboliques et Endocrinologie, F-13385 Marseille, France.
New Microbes New Infect. 2016 Aug 9;14:38-48. doi: 10.1016/j.nmni.2016.07.010. eCollection 2016 Nov.
Butyricimonas phoceensis strain AT9 (= CSUR 1981 = DSM 100664) was isolated from a stool sample from a morbidly obese French patient living in Marseille using the culturomics approach. The genome of this Gram-negative-staining, anaerobic and non-spore forming rod bacillus is 4 736 949 bp long and contains 3947 protein-coding genes. Genomic analysis identified 173 genes as ORFans (4.5%) and 1650 orthologous proteins (42%) not shared with the closest phylogenetic species, Butyricimonas virosa. Its major fatty acid was the branched acid iso-C15:0 (62.3%).
菲奥氏丁酸单胞菌菌株AT9(=CSUR 1981 = DSM 100664)是采用 culturomics 方法从一名居住在马赛的病态肥胖法国患者的粪便样本中分离出来的。这种革兰氏阴性染色、厌氧且不形成芽孢的杆状细菌的基因组长度为4736949 bp,包含3947个蛋白质编码基因。基因组分析确定了173个基因(4.5%)为孤儿基因,以及1650个直系同源蛋白(42%),这些基因和蛋白与亲缘关系最近的物种——维罗氏丁酸单胞菌并不共有。其主要脂肪酸为支链酸异C15:0(62.3%)。