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A role for miR-34 in colon cancer stem cell homeostasis.

作者信息

Rupaimoole Rajesha, Slack Frank J

机构信息

Department of Pathology and Institute of RNA Medicine, Beth Israel Deaconess Medical Center Cancer Center, Harvard Medical School, Boston, MA 02215, USA.

出版信息

Stem Cell Investig. 2016 Aug 24;3:42. doi: 10.21037/sci.2016.08.04. eCollection 2016.

DOI:10.21037/sci.2016.08.04
PMID:27668249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5014853/
Abstract
摘要

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本文引用的文献

1
miRNA Deregulation in Cancer Cells and the Tumor Microenvironment.癌细胞和肿瘤微环境中的微小RNA失调
Cancer Discov. 2016 Mar;6(3):235-46. doi: 10.1158/2159-8290.CD-15-0893. Epub 2016 Feb 10.
2
A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.炎症触发的miR-34a-Numb前馈环调控小肠和结肠癌中的不对称干细胞分裂。
Cell Stem Cell. 2016 Feb 4;18(2):189-202. doi: 10.1016/j.stem.2016.01.006.
3
MicroRNA-34a suppresses the breast cancer stem cell-like characteristics by downregulating Notch1 pathway.微小RNA-34a通过下调Notch1信号通路抑制乳腺癌干细胞样特性。
Cancer Sci. 2015 Jun;106(6):700-708. doi: 10.1111/cas.12656.
4
Tumor suppressor miR-34a targets PD-L1 and functions as a potential immunotherapeutic target in acute myeloid leukemia.肿瘤抑制因子miR-34a靶向程序性死亡配体1(PD-L1),并作为急性髓系白血病潜在的免疫治疗靶点发挥作用。
Cell Signal. 2015 Mar;27(3):443-52. doi: 10.1016/j.cellsig.2014.12.003. Epub 2014 Dec 10.
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Mir-34: a new weapon against cancer?miR-34:抗癌新武器?
Mol Ther Nucleic Acids. 2014 Sep 23;3(9):e194. doi: 10.1038/mtna.2014.47.
6
miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma.miRNA-34 可预防治疗抵抗的 K-ras 和 p53 诱导的肺腺癌细胞癌发生和进展的小鼠模型中的癌症发生和进展。
Cancer Res. 2012 Nov 1;72(21):5576-87. doi: 10.1158/0008-5472.CAN-12-2001. Epub 2012 Sep 10.
7
miR-34 - a microRNA replacement therapy is headed to the clinic.miR-34——一种微小RNA替代疗法即将进入临床应用。
Front Genet. 2012 Jul 2;3:120. doi: 10.3389/fgene.2012.00120. eCollection 2012.
8
Cancer stem cells: an evolving concept.癌症干细胞:一个不断发展的概念。
Nat Rev Cancer. 2012 Jan 12;12(2):133-43. doi: 10.1038/nrc3184.
9
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44.微小 RNA miR-34a 通过直接抑制 CD44 抑制前列腺癌干细胞和转移。
Nat Med. 2011 Feb;17(2):211-5. doi: 10.1038/nm.2284. Epub 2011 Jan 16.
10
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.肠隐窝稳态源自对称分裂的 Lgr5 干细胞之间的中性竞争。
Cell. 2010 Oct 1;143(1):134-44. doi: 10.1016/j.cell.2010.09.016.