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成年脑移植中星形胶质细胞谱系的存活。

Survival of astroglial cell lineage from adult brain transplant.

作者信息

Ignacio V, Collins V P, Suard I M, Jacque C M

机构信息

INSERM U 134, Hôpital de la Salpêtrière, Paris, France.

出版信息

Dev Neurosci. 1989;11(3):175-8.

PMID:2766962
Abstract

We previously described a transplantation model which enables the selective identification of rabbit astroglial cells in sections of mouse brain tissue. In the present paper, we report that cells of the astroglial lineage from an adult transplant are able to survive after implantation into the brain of an immature host. Surviving xenogenic cells are found outside the graft, forming colonies in the host brain parenchyma. However, after 3 months, transplant-derived astrocytes are no longer detected.

摘要

我们之前描述了一种移植模型,该模型能够在小鼠脑组织切片中选择性地识别兔星形胶质细胞。在本文中,我们报告称,来自成年移植体的星形胶质谱系细胞植入未成熟宿主的大脑后能够存活。在移植物外发现了存活的异种细胞,它们在宿主脑实质中形成集落。然而,3个月后,不再检测到移植来源的星形胶质细胞。

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1
Survival of astroglial cell lineage from adult brain transplant.成年脑移植中星形胶质细胞谱系的存活。
Dev Neurosci. 1989;11(3):175-8.
2
Implantation of rabbit embryo brain fragments into newborn mice: integration and survival of xenogeneic astrocytes.将兔胚胎脑片段植入新生小鼠体内:异种星形胶质细胞的整合与存活
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