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欧盟联合研究中心纳米材料库:一个为纳米环境健康与安全研究提供代表性测试材料的独特设施。

The JRC Nanomaterials Repository: A unique facility providing representative test materials for nanoEHS research.

作者信息

Totaro Sara, Cotogno Giulio, Rasmussen Kirsten, Pianella Francesca, Roncaglia Marco, Olsson Heidi, Riego Sintes Juan M, Crutzen Hugues P

机构信息

European Commission, Joint Research Centre, Directorate F - Consumer Product Safety - Via E. Fermi 2749, Ispra, VA, Italy.

European Commission, Joint Research Centre, Directorate F - Consumer Product Safety - Via E. Fermi 2749, Ispra, VA, Italy.

出版信息

Regul Toxicol Pharmacol. 2016 Nov;81:334-340. doi: 10.1016/j.yrtph.2016.08.008. Epub 2016 Sep 23.

DOI:10.1016/j.yrtph.2016.08.008
PMID:27670079
Abstract

The European Commission has established a Nanomaterials Repository that hosts industrially manufactured nanomaterials that are distributed world-wide for safety testing of nanomaterials. In a first instance these materials were tested in the OECD Testing Programme. They have then also been tested in several EU funded research projects. The JRC Repository of Nanomaterials has thus developed into serving the global scientific community active in the nanoEHS (regulatory) research. The unique Repository facility is a state-of-the-art installation that allows customised sub-sampling under the safest possible conditions, with traceable final sample vials distributed world-wide for research purposes. This paper describes the design of the Repository to perform a semi-automated subsampling procedure, offering high degree of flexibility and precision in the preparation of NM vials for customers, while guaranteeing the safety of the operators, and environmental protection. The JRC nanomaterials are representative for part of the world NMs market. Their wide use world-wide facilitates the generation of comparable and reliable experimental results and datasets in (regulatory) research by the scientific community, ultimately supporting the further development of the OECD regulatory test guidelines.

摘要

欧盟委员会建立了一个纳米材料库,该库收纳了在全球范围内分发用于纳米材料安全测试的工业制造纳米材料。首先,这些材料在经合组织测试计划中进行了测试。随后,它们也在多个欧盟资助的研究项目中进行了测试。因此,联合研究中心纳米材料库已发展成为服务于活跃在纳米环境、健康与安全(监管)研究领域的全球科学界。独特的材料库设施是最先进的装置,可在尽可能安全的条件下进行定制化二次采样,并将可溯源的最终样品瓶分发至全球用于研究目的。本文描述了该材料库执行半自动二次采样程序的设计,在为客户准备纳米材料样品瓶时提供高度的灵活性和精确性,同时确保操作人员的安全和环境保护。联合研究中心的纳米材料代表了世界纳米材料市场的一部分。它们在全球的广泛使用有助于科学界在(监管)研究中生成可比且可靠的实验结果和数据集,最终支持经合组织监管测试指南的进一步发展。

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