Zhang B, Lewis S M
Department of Haematology, Royal Postgraduate Medical School, London, U.K.
Eur J Haematol. 1989 Jul;43(1):63-6. doi: 10.1111/j.1600-0609.1989.tb01253.x.
Employing radionuclide scanning, the volume of the spleen, its red cell pool and plasma pool have been measured in vivo, and the relative proportions of cellularity and vascularity of the spleen have been calculated in 51 patients with myeloproliferative and lymphoproliferative disorders. In primary proliferative polycythaemia (polycythaemia vera), the increase of spleen size was attributed mainly to the increase of splenic vascularity; in myelofibrosis and in hairy cell leukaemia, the increase of spleen size was associated with increase in both splenic vascularity and cellularity, whilst in CGL and CLL the increase was attributed more to cellularity than to vascularity.
采用放射性核素扫描技术，对51例骨髓增殖性和淋巴增殖性疾病患者进行了脾脏体积、红细胞池和血浆池的活体测量，并计算了脾脏细胞成分和血管成分的相对比例。在原发性增殖性红细胞增多症（真性红细胞增多症）中，脾脏大小的增加主要归因于脾血管增多；在骨髓纤维化和毛细胞白血病中，脾脏大小的增加与脾血管增多和细胞成分增多均有关，而在慢性粒细胞白血病和慢性淋巴细胞白血病中，脾脏大小的增加更多归因于细胞成分增多而非血管增多。
