Department of Cell and Developmental Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, England.
Department of Cell and Developmental Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, England.
Dev Cell. 2016 Sep 26;38(6):579-83. doi: 10.1016/j.devcel.2016.09.006.
Computational modeling of tissue morphogenesis reveals how spatiotemporal patterns of gene activity control tissue shape by introducing several types of tissue conflict. These conflicts reflect genetic modulation of processes that influence the cellular mechanical properties and may underlie the enormous diversity of forms that have evolved in plants and animals.
组织形态发生的计算建模揭示了时空基因活性模式如何通过引入几种类型的组织冲突来控制组织形状。这些冲突反映了遗传调节过程的影响,这些过程会影响细胞的机械特性,并可能是植物和动物中已经进化出的巨大形态多样性的基础。