Balaban N P, Suleimanova A D, Valeeva L R, Shakirov E V, Sharipova M R
Kazan (Volga Region) Federal University, Kazan, 420008, Russia.
Biochemistry (Mosc). 2016 Aug;81(8):785-93. doi: 10.1134/S0006297916080010.
β-Propeller phytases of Bacillus are unique highly conservative and highly specific enzymes capable of cleaving insoluble phytate compounds. In this review, we analyzed data on the properties of these enzymes, their differences from other phytases, and their unique spatial structures and substrate specificities. We considered influences of different factors on the catalytic activity and thermostability of these enzymes. There are few data on the hydrolysis mechanism of these enzymes, which makes it difficult to analyze their mechanism of action and their final products. We analyzed the available data on hydrolysis by β-propeller phytases of calcium complexes with myo-inositol hexakisphosphate.
芽孢杆菌的β-螺旋桨植酸酶是一类独特的、高度保守且高度特异的酶，能够裂解不溶性植酸盐化合物。在本综述中，我们分析了有关这些酶的性质、它们与其他植酸酶的差异、独特的空间结构和底物特异性的数据。我们考虑了不同因素对这些酶的催化活性和热稳定性的影响。关于这些酶的水解机制的数据很少，这使得分析它们的作用机制和最终产物变得困难。我们分析了有关β-螺旋桨植酸酶对钙与肌醇六磷酸复合物水解的现有数据。
