Scholten-Jaegers Sonja M H J, Nieuwenhuis Marianne K, van Baar Magriet E, Niemeijer Anuschka S, Hiddingh Jakob, Beerthuizen Gerard I J M
From the *Burn Centre, Martini Hospital, Groningen, The Netherlands; †Association of Dutch Burn Centres, Burn Centre, Martini Hospital, Groningen, The Netherlands; and ‡Association of Dutch Burn Centres, Burn Centre, Maasstad Hospital, Rotterdam, The Netherlands.
J Burn Care Res. 2017 Jan/Feb;38(1):e432-e442. doi: 10.1097/BCR.0000000000000448.
In this study, the outcome of treatment with Flammacerium in burn patients is studied. The retrospective study involved patients with acute burns admitted to the Burn Centre of Martini Hospital, Groningen, The Netherlands, between 2009 and 2014. The outcome parameters were mortality, complications (noninfectious and infectious), need of surgery, and length of stay. The group of patients consisted of 853 patients, of which 554 were male (64.9%). There were 23 patients with a total burn size of 40% TBSA or more (2.7%). In total, 13 of the 853 patients (1.5%) died, and none of them were children (<16 years). The overall mortality in the group of patient with burns >40% TBSA was 30.4%. In the elderly group (>70 years), the mortality rate was 6.3%. Treatment with Flammacerium is applicable in all thermal burn patients. Especially children, elderly patients, and patients with severe burns can benefit from a more conservative treatment with Flammacerium whereby the first operation can be postponed until the patient is stabilized and in which the wounds can be covered directly with skin transplants.
在本研究中，对烧伤患者使用Flammacerium进行治疗的结果进行了研究。这项回顾性研究纳入了2009年至2014年间入住荷兰格罗宁根马蒂尼医院烧伤中心的急性烧伤患者。结果参数包括死亡率、并发症（非感染性和感染性）、手术需求和住院时间。患者组由853名患者组成，其中554名男性（64.9%）。有23名患者烧伤总面积达40%TBSA或更高（2.7%）。853名患者中共有13名（1.5%）死亡，且均非儿童（<16岁）。烧伤面积>40%TBSA的患者组总体死亡率为30.4%。老年组（>70岁）死亡率为6.3%。Flammacerium治疗适用于所有热烧伤患者。特别是儿童、老年患者和重度烧伤患者可从使用Flammacerium的更保守治疗中获益，借此首次手术可推迟至患者病情稳定，且伤口可直接用皮肤移植覆盖。
